Tyk2-IN-20

Name: Tyk2-IN-20
Brand: Adooq Bioscience
SKU: A33364
Rating: 5 (288 reviews)

Catalog No.: A33364

Tyk2 Inhibitor

Tyk2-IN-20 is a highly potent inhibitor of Tyk2, exhibiting an IC50 of less than 5 nM. Additionally, it demonstrates inhibitory activity against JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is valuable for investigating inflammatory diseases and related signaling pathways, making it a critical tool for research in immunology and therapeutic development.

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Biological Activity

Description	Tyk2-IN-20 is a highly potent inhibitor of Tyk2, exhibiting an IC50 of less than 5 nM. Additionally, it demonstrates inhibitory activity against JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is valuable for investigating inflammatory diseases and related signaling pathways, making it a critical tool for research in immunology and therapeutic development.

Product Information

Catalog Num	A33364
Formula	C24H25N7O2
Molecular Weight	443.50
CAS Number	3058568-08-1
SMILES	C[C@@H]([C@@](C#N)(C1CC1)C2=O)CN2C3=NC(C4=CN(C5CC6(COC6)C5)N=C4)=CN7C3=CC=N7

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