Tyrphostin AG213 is a selective inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.85 μM, targeting its protein tyrosine kinase activity. In addition to its primary function, Tyrphostin AG213 also inhibits tyrosine kinase activity with an IC50 of 2.4 μM and topoisomerase II, exhibiting an IC100 of 50 μM. This compound has been shown to induce non-apoptotic programmed cell death in tumor cells, making it a valuable tool for cancer research and potential therapeutic applications.
Tyrphostin AG213 is a selective inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.85 μM, targeting its protein tyrosine kinase activity. In addition to its primary function, Tyrphostin AG213 also inhibits tyrosine kinase activity with an IC50 of 2.4 μM and topoisomerase II, exhibiting an IC100 of 50 μM. This compound has been shown to induce non-apoptotic programmed cell death in tumor cells, making it a valuable tool for cancer research and potential therapeutic applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
