Ulevostinag

Catalog No.: A65582
STING Agonist
Ulevostinag is a potent STING (stimulator of interferon genes) agonist that activates the immune response through the modulation of cyclic dinucleotide pathways. By stimulating STING, Ulevostinag enhances the production of type I interferons, which play a crucial role in the anti-tumor immune response. This compound is primarily utilized in research focused on immuno-oncology, particularly in the exploration of new therapeutic strategies for cancer treatment.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUlevostinag is a potent STING (stimulator of interferon genes) agonist that activates the immune response through the modulation of cyclic dinucleotide pathways. By stimulating STING, Ulevostinag enhances the production of type I interferons, which play a crucial role in the anti-tumor immune response. This compound is primarily utilized in research focused on immuno-oncology, particularly in the exploration of new therapeutic strategies for cancer treatment.
Product Information
Catalog NumA65582
FormulaC20H22F2N10O9P2S2
Molecular Weight710.52
CAS Number2082743-96-0
SMILESF[C@H]1[C@](O[P@](S)(OC[C@](O[C@](N2C3=NC=NC(N)=C3N=C2)([H])[C@H]4F)([H])[C@@]4([H])O5)=O)([H])[C@@](N6C(NC(N)=NC7=O)=C7N=C6)([H])O[C@]1([H])CO[P@]5(S)=O
SynonymsMK-1454
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