Upadacitinib tartrate tetrahydrate is a selective inhibitor of Janus kinase 1 (JAK1) with an IC50 value of 43 nM. It exhibits approximately 74-fold selectivity for JAK1 over JAK2 in assays utilizing specific cytokines. This compound is widely applicable in research focused on autoimmune disorders, providing insights into the modulation of immune responses through JAK1 inhibition.
Upadacitinib tartrate tetrahydrate is a selective inhibitor of Janus kinase 1 (JAK1) with an IC50 value of 43 nM. It exhibits approximately 74-fold selectivity for JAK1 over JAK2 in assays utilizing specific cytokines. This compound is widely applicable in research focused on autoimmune disorders, providing insights into the modulation of immune responses through JAK1 inhibition.
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