USP7-IN-1

Catalog No.: A12813

USP7 inhibitor

USP7-IN-1

USP7-IN-1 Chemical Structure

CAS NO. 1381291-36-6

USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM; less or no inhibition on USP5, USP8, Uch-L1, Uch-L3 and Caspase(IC50>200 uM); HCT116 cell viability GI50 is 67 uM.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $320.00

Special Price $256.00

10 mg

Regular Price: $500.00

Special Price $400.00

50 mg

Regular Price: $1,400.00

Special Price $1,120.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM; less or no inhibition on USP5, USP8, Uch-L1, Uch-L3 and Caspase(IC50>200 uM); HCT116 cell viability GI50 is 67 uM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.48 mL 117.4 mL 234.79 mL
0.5 mM 4.7 mL 23.48 mL 46.96 mL
1 mM 2.35 mL 11.74 mL 23.48 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12813
Actions Inhibitor
CAS No. 1381291-36-6
Formula C23H24ClN3O3
M. Wt 425.91
Purity >98%
SMILES ClC1=CC=C(C(N(CC2(O)CCN(C(CCC3=CC=CC=C3)=O)CC2)C=N4)=O)C4=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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