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Val-CDCA

Catalog No.: A95247
Drug Derivative
Val-CDCA is a conjugate of chenodeoxycholate (CDCA) and C-24 L-Valine, primarily targeting the sodium-taurocholate cotransporting polypeptide (NTCP). This compound effectively inhibits taurocholate uptake in human NTCP-stably transfected HEK293 cells, indicating its potential utility in research related to hepatitis B virus (HBV) infection. Val-CDCA serves as a valuable tool for studies investigating bile acid transport and its implications in liver diseases.
Val-CDCA 1640013-00-8 Drug Derivative
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVal-CDCA is a conjugate of chenodeoxycholate (CDCA) and C-24 L-Valine, primarily targeting the sodium-taurocholate cotransporting polypeptide (NTCP). This compound effectively inhibits taurocholate uptake in human NTCP-stably transfected HEK293 cells, indicating its potential utility in research related to hepatitis B virus (HBV) infection. Val-CDCA serves as a valuable tool for studies investigating bile acid transport and its implications in liver diseases.
Product Information
Catalog NumA95247
FormulaC29H49NO5
Molecular Weight491.70
CAS Number1640013-00-8
SMILESO[C@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N[C@H](C(O)=O)C(C)C)=O)C)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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