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$0.00 Biological Activity
Valecobulin (CKD516) is a valine prodrug of (S516) and a vascular disrupting agent (VDA). Valecobulin is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.64 mL | 93.18 mL | 186.36 mL |
| 0.5 mM | 3.73 mL | 18.64 mL | 37.27 mL |
| 1 mM | 1.86 mL | 9.32 mL | 18.64 mL |
| 5 mM | 0.37 mL | 1.86 mL | 3.73 mL |
*The above data is based on the productmolecular weight 536.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21242 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1188371-47-2 |
| Formula | C26H28N6O5S |
| M. Wt | 536.6 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | CKD-516 |
| SMILES | CC(C)[[email protected]](N)C(NC1=NC(C2=CC=C(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)C(N4N=CN=C4)=C2)=CS1)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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