Signaling Pathway
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| Discription | Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC50 =0.46 nM and IC50 =1~10 nM to HIV isolates (n=52). |
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| Catalog Num | A10971 |
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| Formula | C28H38F3N5O2.C4H6O5 |
| Molecular Weight | 667.7 |
| CAS Number | 541503-81-5 |
| SMILES | C[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 121 mg/mL (181.21 mM) | |
| Water | 34 mg/mL (50.92 mM) | ||
| Ethanol | 121 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.98 mL | 74.88 mL | 149.77 mL |
| 0.5 mM | 3 mL | 14.98 mL | 29.95 mL |
| 1 mM | 1.5 mL | 7.49 mL | 14.98 mL |
| 5 mM | 0.3 mL | 1.5 mL | 3 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
