Vorinostat-d5 is a deuterium-labeled form of Vorinostat, a potent pan-inhibitor of histone deacetylases (HDACs), specifically targeting HDAC1, HDAC2, and HDAC3 (Class I), HDAC7 (Class II), and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. It effectively induces apoptosis in cancer cells and serves as an inhibitor of human papillomavirus (HPV)-18 DNA amplification. Vorinostat-d5 is valuable for research applications focused on epigenetics, cancer therapy, and virology.
Vorinostat-d5 is a deuterium-labeled form of Vorinostat, a potent pan-inhibitor of histone deacetylases (HDACs), specifically targeting HDAC1, HDAC2, and HDAC3 (Class I), HDAC7 (Class II), and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. It effectively induces apoptosis in cancer cells and serves as an inhibitor of human papillomavirus (HPV)-18 DNA amplification. Vorinostat-d5 is valuable for research applications focused on epigenetics, cancer therapy, and virology.
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