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VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.85 mL | 134.26 mL | 268.53 mL |
| 0.5 mM | 5.37 mL | 26.85 mL | 53.71 mL |
| 1 mM | 2.69 mL | 13.43 mL | 26.85 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.37 mL |
*The above data is based on the productmolecular weight 372.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20102 |
|---|---|
| Actions | Antagonist |
| CAS No. | 449173-19-7 |
| Formula | C17H29N2O5P |
| M. Wt | 372.4 |
| Purity | >98% |
| Synonyms | VPC23019, VPC-23019 |
| SMILES | O=C(NC1=CC=CC(CCCCCCCC)=C1)[[email protected]](N)COP(O)(O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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