VPC 23019

Catalog No.: A20102

S1P antagonist

VPC 23019

VPC 23019 Chemical Structure

CAS NO. 449173-19-7

VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).

Availability: In stock

Package Price Qty
1 mg
$450.00
5 mg
$950.00
10 mg
$1,600.00
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Biological Activity

VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.85 mL 134.26 mL 268.53 mL
0.5 mM 5.37 mL 26.85 mL 53.71 mL
1 mM 2.69 mL 13.43 mL 26.85 mL
5 mM 0.54 mL 2.69 mL 5.37 mL

*The above data is based on the productmolecular weight 372.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20102
Actions Antagonist
CAS No. 449173-19-7
Formula C17H29N2O5P
M. Wt 372.4
Purity >98%
Synonyms VPC23019, VPC-23019
SMILES O=C(NC1=CC=CC(CCCCCCCC)=C1)[[email protected]](N)COP(O)(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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