Signaling Pathway
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| Discription | Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,which does not significantly inhibit the isoforms of class I as well as class II PI3Ks. | ||
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| Targets |
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| Catalog Num | A15874 |
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| Formula | C21H24ClN7O |
| Molecular Weight | 425.91 |
| CAS Number | 1383716-33-3 |
| SMILES | OC(C)(C)CNC(N=C1CC2CC2)=NC=C1C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3 |
| Synonyms | PS34 IN1, VPS34IN1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 73 mg/mL (171.4 mM) | |
| Water | Insoluble | ||
| Ethanol | 73 mg/mL (171.4 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.48 mL | 117.4 mL | 234.79 mL |
| 0.5 mM | 4.7 mL | 23.48 mL | 46.96 mL |
| 1 mM | 2.35 mL | 11.74 mL | 23.48 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
