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PI3K/mTOR inhibitor

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Catalog No. A12480

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
VS-5584 10mg A12480-10

Regular Price: $120.00

Special Price: $108.00

VS-5584 25mg A12480-25

Regular Price: $250.00

Special Price: $225.00

VS-5584 50mg A12480-50

Regular Price: $400.00

Special Price: $360.00

VS-5584 10mM * 1mL in DMSO A12480-10mM-D

Regular Price: $95.00

Special Price: $85.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.


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Chemical Information

Catalog Num A12480
Actions Inhibitor
M. Wt 354.41
Formula C17H22N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1246560-33-7
Synonyms SB2343, VS5584, SB-2343, SB 2343

Biological Activity

VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
2.6 nM2.7 nM3.0 nM3.4 nM21 nM


Solubility (25°C) * In vitro DMSO 71 mg/mL (200.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (8.46 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.22 mL 141.08 mL 282.16mL
0.5 mM 5.64 mL 28.22 mL 56.43 mL
1 mM 2.82 mL 14.11 mL 28.22 mL
5 mM 0.56 mL 2.82 mL 5.64 mL

*The above data is based on the productmolecular weight 354.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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