VU 0364739 hydrochloride is a selective inhibitor of phospholipase D2 (PLD2), exhibiting an IC50 of 20 nM for PLD2 while having significantly lower activity against PLD1 (IC50 of 1500 nM). This compound has been shown to induce apoptosis, making it a valuable reagent for cancer research. Its specificity and potent biological activity position VU 0364739 as an important tool for studying PLD2's role in cellular processes and cancer pathophysiology.
VU 0364739 hydrochloride is a selective inhibitor of phospholipase D2 (PLD2), exhibiting an IC50 of 20 nM for PLD2 while having significantly lower activity against PLD1 (IC50 of 1500 nM). This compound has been shown to induce apoptosis, making it a valuable reagent for cancer research. Its specificity and potent biological activity position VU 0364739 as an important tool for studying PLD2's role in cellular processes and cancer pathophysiology.
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