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Publications citing Adooq Products
VX-702 Citations (1)
Chemical Information
| Catalog Num | A10982 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 404.3 |
| Formula | C19H12F4N4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 479543-46-9 |
| Synonyms | VX702, VX 702 |
| SMILES code | C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F |
| Chemical Name | 6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide |
Description |
VX-702 is an orally bioavailable inhibitor of p38 MAP kinase that inhibits platelet agonist induced p38 activation (IC50= 4 to 20 nM). | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.73 mL | 123.67 mL | 247.34mL |
| 0.5 mM | 4.95 mL | 24.73 mL | 49.47 mL |
| 1 mM | 2.47 mL | 12.37 mL | 24.73 mL |
| 5 mM | 0.49 mL | 2.47 mL | 4.95 mL |
*The above data is based on the productmolecular weight 404.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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