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VX-702

Catalog No.: A10982
p38 MAPK inhibitor
Adooq's VX-702 has been cited by 1 publications
VX-702 is an orally bioavailable inhibitor of p38 MAP kinase that inhibits platelet agonist induced p38 activation (IC50= 4 to 20 nM).
VX-702
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Size Price Stock Qty
5mg
$35.00
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10mg
$35.00
In stock
25mg
$70.00
In stock
50mg
$95.00
In stock
100mg
$185.00
In stock
200mg
$310.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VX-702 has been cited by 1 publications
  • Wei-Chun HuangFu, etc. Inflammatory signaling compromises cell responses to interferon alpha. Oncogene. 2012 Jan 12; 31(2): 161?€?172.
    • Biological Activity
    Discription VX-702 is an orally bioavailable inhibitor of p38 MAP kinase that inhibits platelet agonist induced p38 activation (IC50= 4 to 20 nM).
    Product Information
    Catalog Num A10982
    Formula C19H12F4N4O2
    Molecular Weight 404.3
    CAS Number 479543-46-9, 745833-23-2
    SMILES C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F
    Synonyms VX702, VX 702
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 77 mg/mL (190.45 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.73 mL 123.67 mL 247.34 mL
    0.5 mM 4.95 mL 24.73 mL 49.47 mL
    1 mM 2.47 mL 12.37 mL 24.73 mL
    5 mM 0.49 mL 2.47 mL 4.95 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    MAPK > p38-MAPK
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