VX-765 (Belnacasan)

Catalog No.: A10984

Caspase-1/4 inhibitor

VX-765 (Belnacasan)

VX-765 (Belnacasan) Chemical Structure

CAS NO. 273404-37-8

VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $98.00

Special Price $78.40

50 mg

Regular Price: $250.00

Special Price $200.00

100 mg

Regular Price: $450.00

Special Price $360.00

10mM * 1mL in DMSO
$75.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18.
Targets
Caspase-4 (Cell-free assay) Caspase-1 (Cell-free assay)
<0.6 nM(Ki)0.8 nM(Ki)
In vitro DMSO 100 mg/mL heating (196.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL heating (196.46 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.65 mL 98.23 mL 196.46 mL
0.5 mM 3.93 mL 19.65 mL 39.29 mL
1 mM 1.96 mL 9.82 mL 19.65 mL
5 mM 0.39 mL 1.96 mL 3.93 mL

*The above data is based on the productmolecular weight 509.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10984
Actions Inhibitor
M. Wt 509.0
Formula C24H33ClN4O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 273404-37-8
Synonyms VX765
SMILES CCO[[email protected]]1[[email protected]](CC(=O)O1)NC(=O)[[email protected]@H]2CCCN2C(=O)[[email protected]](C(C)(C)C)NC(=O)C3=CC(=C(C=C3)N)Cl

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