Total item
Cart Subtotal
$0.00 Biological Activity
VX-770 (Ivacaftor) is known as a CFTR potentiator.
Targets
| F508del-CFTR (Fisher rat thyroid cells) | G551D-CFTR (Fisher rat thyroid cells) | |||
| 25 nM(EC50) | 100 nM(EC50) |
| In vitro | DMSO | 78 mg/mL (198.73 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.48 mL | 127.39 mL | 254.78 mL |
| 0.5 mM | 5.1 mL | 25.48 mL | 50.96 mL |
| 1 mM | 2.55 mL | 12.74 mL | 25.48 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
*The above data is based on the productmolecular weight 392.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10985 |
|---|---|
| Actions | Activator |
| M. Wt | 392.5 |
| Formula | C24H28N2O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 873054-44-5, 121911-71-5 |
| Synonyms | Kalydeco, VX770 |
| SMILES | CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy VX-770 (Ivacaftor) | VX-770 (Ivacaftor) Supplier | purchase VX-770 (Ivacaftor) | VX-770 (Ivacaftor) cost | VX-770 (Ivacaftor) manufacturer | order VX-770 (Ivacaftor) | VX-770 (Ivacaftor) distributor | buy 873054-44-5, 121911-71-5| 873054-44-5, 121911-71-5 Supplier | purchase 873054-44-5, 121911-71-5 | 873054-44-5, 121911-71-5 cost | 873054-44-5, 121911-71-5 manufacturer | order 873054-44-5, 121911-71-5 | 873054-44-5, 121911-71-5 distributor
Adooq Quality Guarantee
We promise all products perform as described.