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VX-770 (Ivacaftor)

Catalog No.: A10985
CFTR activator
Adooq's VX-770 (Ivacaftor) has been cited by 2 publications
VX-770 (Ivacaftor) is known as a CFTR potentiator.
VX-770 (Ivacaftor)
Grouped product items
Product Name Price Stock Qty
VX-770 5mg
$70.00
In stock
VX-770 10mg
$120.00
In stock
VX-770 50mg
$380.00
In stock
VX-770 100mg
$650.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VX-770 (Ivacaftor) has been cited by 2 publications
  • Daichi Hinata, .et al. , Int J Mol Sci, 2023, Jan 24;24(3):2305 PMID: 36768629
  • Okiyoneda T, .et al. , Dev Cell, 2018, Mar 26;44(6):694-708.e7 PMID: 29503157
    • Biological Activity
    Discription VX-770 (Ivacaftor) is known as a CFTR potentiator.
    Targets
    Target Value
    Product Information
    Catalog Num A10985
    Formula C24H28N2O3
    Molecular Weight 392.5
    CAS Number 873054-44-5, 121911-71-5
    SMILES CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C
    Synonyms Kalydeco, VX770
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO 69 mg/mL (175.8 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.48 mL 127.39 mL 254.78 mL
    0.5 mM 5.1 mL 25.48 mL 50.96 mL
    1 mM 2.55 mL 12.74 mL 25.48 mL
    5 mM 0.51 mL 2.55 mL 5.1 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
    Membrane Transporters-Ion Channels > CFTR
    Membrane Transporters-Ion Channels > Chloride Channels
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