WAY-181187 oxalate is a selective full agonist of the 5-HT6 receptor, exhibiting a binding affinity with a Ki of 2.2 nM and an effective concentration for half-maximal activation (EC50) of 6.6 nM. This compound engages 5-HT6 receptor-mediated signaling pathways, influencing cAMP, Fyn, and ERK1/2 kinase activity. It serves as a valuable tool for research into neuropharmacology and potential therapeutic applications targeting cognitive disorders.
WAY-181187 oxalate is a selective full agonist of the 5-HT6 receptor, exhibiting a binding affinity with a Ki of 2.2 nM and an effective concentration for half-maximal activation (EC50) of 6.6 nM. This compound engages 5-HT6 receptor-mediated signaling pathways, influencing cAMP, Fyn, and ERK1/2 kinase activity. It serves as a valuable tool for research into neuropharmacology and potential therapeutic applications targeting cognitive disorders.
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