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$0.00 - Greish K, .et al. Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer, J Control Release, 2018, Dec 10;291:184-195 PMID: 30367922
Biological Activity
WIN 55,212-2 is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling.
| In vitro | DMSO | 90 mg/mL (172.21 mM) | |
| Water | 90 mg/mL (172.21 mM) | ||
| Ethanol | 18 mg/mL (34.43 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.14 mL | 95.68 mL | 191.35 mL |
| 0.5 mM | 3.83 mL | 19.14 mL | 38.27 mL |
| 1 mM | 1.91 mL | 9.57 mL | 19.14 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.83 mL |
*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11932 |
|---|---|
| Actions | Agonist |
| CAS No. | 131543-23-2 |
| Formula | C27H26N2O3.CH3SO3H |
| M. Wt | 522.6 |
| Purity | >98% |
| Synonyms | (R)-(+)-WIN 55212 |
| SMILES | CC1=C(C2=C3N1[[email protected]@H](COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65.CS(=O)(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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