WNK463

Catalog No.: A16205

pan-WNK-kinase inhibitor

WNK463

WNK463 Chemical Structure

CAS NO. 2012607-27-9

WNK463 is an orally bioavailable pan-WNK-kinase inhibitor.

Availability: In stock

Package Price Qty
1 mg
$110.00
5 mg
$175.00
10 mg
$285.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Lu DC, .et al. The role of WNK in modulation of KCl cotransport activity in red cells from normal individuals and patients with sickle cell anaemia, Pflugers Arch, 2019, Dec;471(11-12):1539-1549 PMID: 31729557

Biological Activity

WNK463 is an orally bioavailable pan-WNK-kinase inhibitor.
Targets
WNK-kinase
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.58 mL 107.88 mL 215.77 mL
0.5 mM 4.32 mL 21.58 mL 43.15 mL
1 mM 2.16 mL 10.79 mL 21.58 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 463.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16205
Actions Inhibitor
M. Wt 463.46
Formula C21H24F3N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2012607-27-9
Synonyms WNK-463, WNK 463
SMILES CC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F

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