WNK463
WNK463 is an orally bioavailable pan-WNK-kinase inhibitor.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's WNK463 has been cited by 1 publications
- Lu DC, .et al. , Pflugers Arch, 2019, Dec;471(11-12):1539-1549 PMID: 31729557
Biological Activity
| Description | WNK463 is an orally bioavailable pan-WNK-kinase inhibitor. | ||
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Product Information
| Catalog Num | A16205 |
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| Formula | C21H24F3N7O2 |
| Molecular Weight | 463.46 |
| CAS Number | 2012607-27-9 |
| SMILES | CC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F |
| Synonyms | WNK-463, WNK 463 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 81 mg/mL (174.77 mM) | |
| Water | Insoluble | ||
| Ethanol | 81 mg/mL (174.77 mM) | ||
| In vivo | 5% DMSO+30%PEG 300+5% Tween 80+ddH2O | 7 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.58 mL | 107.88 mL | 215.77 mL |
| 0.5 mM | 4.32 mL | 21.58 mL | 43.15 mL |
| 1 mM | 2.16 mL | 10.79 mL | 21.58 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.32 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
