WP1066

Catalog No.: A11795

JAK Inhibitor

WP1066

WP1066 Chemical Structure

CAS NO. 857064-38-1

WP1066 is a novel JAK2 inhibitor and it suppresses proliferation and induces apoptosis in eythroid human cells carrying the JAK2 V617F mutation.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $60.00

Special Price $54.00

25 mg

Regular Price: $140.00

Special Price $126.00

50 mg

Regular Price: $210.00

Special Price $189.00

10mM * 1mL in DMSO

Regular Price: $70.00

Special Price $63.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

WP1066 is a novel JAK2 inhibitor and it suppresses proliferation and induces apoptosis in eythroid human cells carrying the JAK2 V617F mutation.
Targets
JAK2 (HEL cells) STAT3 (HEL cells)
2.3 μM2.43 μM
In vitro DMSO 71 mg/mL (199.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.07 mL 140.37 mL 280.74 mL
0.5 mM 5.61 mL 28.07 mL 56.15 mL
1 mM 2.81 mL 14.04 mL 28.07 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11795
Actions Inhibitor
M. Wt 356.2
Formula C17H14BrN3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 857064-38-1
Synonyms WP 1066, WP-1066
SMILES C[[email protected]@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N

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