WS-383

Catalog No.: A21483

DCN1-UBC12 interaction inhibitor

WS-383

WS-383 Chemical Structure

CAS NO. 2247544-02-9

WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.31 mL 200.62 mL
0.5 mM 4.01 mL 20.06 mL 40.12 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21483
Actions Inhibitor
M. Wt 498.46
Formula C18H21Cl2N9S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2247544-02-9
Synonyms WS383, WS 383
SMILES CN(C)CCN1N=NN=C1SC2=CC(C)=NC3=NC(SCC4=CC=C(Cl)C=C4)=NN23.Cl

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