WZ4003

Catalog No.: A14312

NUAK kinase inhibitor

WZ4003

WZ4003 Chemical Structure

CAS NO. 1214265-58-3

WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2

Availability: In stock

Package Price Qty
10 mg
$75.00
25 mg
$135.00
50 mg
$180.00
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Biological Activity

WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2
Targets
NUAK1 (Cell-free assay) NUAK2 (Cell-free assay)
20 nM100 nM
In vitro DMSO 7 mg/mL (14.08 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.12 mL 100.61 mL 201.21 mL
0.5 mM 4.02 mL 20.12 mL 40.24 mL
1 mM 2.01 mL 10.06 mL 20.12 mL
5 mM 0.4 mL 2.01 mL 4.02 mL

*The above data is based on the productmolecular weight 496.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14312
Actions Inhibitor
CAS No. 1214265-58-3
Formula C25H29ClN6O3
M. Wt 496.99
Solubility DMSO
Purity >98%
Synonyms WZ 4003, WZ-4003
SMILES CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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