WZ4003

Catalog No.: A14312

NUAK kinase inhibitor

WZ4003

WZ4003 Chemical Structure

CAS NO. 1214265-58-3

WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2

Availability: In stock

Package Price Qty
10 mg
$100.00
25 mg
$200.00
50 mg
$350.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

WZ4003 is a highly specific NUAK kinase inhibitor with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2
Targets
NUAK1 (Cell-free assay) NUAK2 (Cell-free assay)
20 nM100 nM
In vitro DMSO 7 mg/mL (14.08 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.12 mL 100.61 mL 201.21 mL
0.5 mM 4.02 mL 20.12 mL 40.24 mL
1 mM 2.01 mL 10.06 mL 20.12 mL
5 mM 0.4 mL 2.01 mL 4.02 mL

*The above data is based on the productmolecular weight 496.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14312
Actions Inhibitor
M. Wt 496.99
Formula C25H29ClN6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1214265-58-3
Synonyms WZ 4003, WZ-4003
SMILES CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC

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