Xanthine oxidase-IN-17

Catalog No.: A78157
XOD Inhibitor
Xanthine oxidase-IN-17 is a selective inhibitor of xanthine oxidase (XOD), demonstrating an IC50 of 298 nM and a Ki of 167 nM. By inhibiting XOD, it effectively reduces the generation of superoxide radicals and decreases uric acid production. This compound exhibits no cytotoxic effects on AML-12 hepatocyte cells and is valuable for research addressing hyperuricemia and gout.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXanthine oxidase-IN-17 is a selective inhibitor of xanthine oxidase (XOD), demonstrating an IC50 of 298 nM and a Ki of 167 nM. By inhibiting XOD, it effectively reduces the generation of superoxide radicals and decreases uric acid production. This compound exhibits no cytotoxic effects on AML-12 hepatocyte cells and is valuable for research addressing hyperuricemia and gout.
Product Information
Catalog NumA78157
FormulaC17H16O4
Molecular Weight284.31
CAS Number185522-92-3
SMILESCOC1=CC=C(C(/C=C/C2=CC=C(O)C=C2)=O)C(OC)=C1
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