Xanthine oxidase-IN-5 is a potent and orally active inhibitor of xanthine oxidase (XO), exhibiting an IC50 value of 0.70 μM. This compound demonstrates favorable ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 has shown significant hypouricemic effects in hyperuricemic rat models, making it a valuable tool for research into conditions related to elevated uric acid levels.
Xanthine oxidase-IN-5 is a potent and orally active inhibitor of xanthine oxidase (XO), exhibiting an IC50 value of 0.70 μM. This compound demonstrates favorable ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 has shown significant hypouricemic effects in hyperuricemic rat models, making it a valuable tool for research into conditions related to elevated uric acid levels.
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