XEN103 is a selective inhibitor of stearoyl-CoA desaturase 1 (SCD1), exhibiting IC50 values of 14 nM and 12 nM against mouse SCD1 and human SCD1 in HepG2 cells, respectively. This compound plays a significant role in research related to obesity and type 2 diabetes by modulating lipid metabolism. Additionally, XEN103 has been shown to induce sebaceous gland atrophy in murine models, providing further avenues for study in dermatological and metabolic disorders.
XEN103 is a selective inhibitor of stearoyl-CoA desaturase 1 (SCD1), exhibiting IC50 values of 14 nM and 12 nM against mouse SCD1 and human SCD1 in HepG2 cells, respectively. This compound plays a significant role in research related to obesity and type 2 diabetes by modulating lipid metabolism. Additionally, XEN103 has been shown to induce sebaceous gland atrophy in murine models, providing further avenues for study in dermatological and metabolic disorders.
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