Fig. 1 · Structure
Documents & Downloads
XEN103
Cat. No.
A77857
CAS
840489-44-3
SCD1 Inhibtior
XEN103 is a selective inhibitor of stearoyl-CoA desaturase 1 (SCD1), exhibiting IC50 values of 14 nM and 12 nM against mouse SCD1 and human SCD1 in HepG2 cells, respectively. This compound plays a significant role in research related to obesity and type 2 diabetes by modulating lipid metabolism. Additionally, XEN103 has been shown to induce sebaceous gland atrophy in murine models, providing further avenues for study in dermatological and metabolic disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 840489-44-3 |
| Applications | SCD1 Inhibtior |
| Formula | C22H23F4N5O2 |
| Molecular Weight | 465.44 |
| SMILES | O=C(C1=NN=C(N2CCN(CC2)C(C3=CC(F)=CC=C3C(F)(F)F)=O)C=C1)NCCC4CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.