XL-147 (Pilaralisib)

Catalog No.: A15283

PI3K Inhibitor

XL-147 (Pilaralisib) Chemical Structure

CAS NO. 934526-89-3

XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.
Targets
PI3Kγ PI3Kβ PI3Kδ PI3Kα
23 nM36 nM36 nM39 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.48 mL 92.42 mL 184.84 mL
0.5 mM 3.7 mL 18.48 mL 36.97 mL
1 mM 1.85 mL 9.24 mL 18.48 mL
5 mM 0.37 mL 1.85 mL 3.7 mL

*The above data is based on the productmolecular weight 541.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15283
Actions Inhibitor
M. Wt 541.02
Formula C25H25ClN6O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 934526-89-3
Synonyms SAR245408, XL 147, XL147, SAR-245408, SAR 245408, pilaralisib
SMILES CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N

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