XL-147 (Pilaralisib)

Catalog No.: A15283

PI3K Inhibitor

XL-147 (Pilaralisib)

XL-147 (Pilaralisib) Chemical Structure

CAS NO. 934526-89-3

XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.

Availability: In stock

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5 mg

Regular Price: $60.00

Special Price $48.00

10 mg

Regular Price: $100.00

Special Price $80.00

25 mg

Regular Price: $200.00

Special Price $160.00

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Biological Activity

XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases.
23 nM36 nM36 nM39 nM
In vitro (25°C) DMSO Warmed: 92 mg/mL (170.04 mM)
Water Insoluble
Ethanol Insoluble
In vivo 10 mM HCl in sterile water 0.4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.48 mL 92.42 mL 184.84 mL
0.5 mM 3.7 mL 18.48 mL 36.97 mL
1 mM 1.85 mL 9.24 mL 18.48 mL
5 mM 0.37 mL 1.85 mL 3.7 mL

*The above data is based on the productmolecular weight 541.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15283
Actions Inhibitor
CAS No. 934526-89-3
Formula C25H25ClN6O4S
M. Wt 541.02
Purity >98%
Synonyms SAR245408, XL 147, XL147, SAR-245408, SAR 245408, pilaralisib

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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