XL147 analogue

Catalog No.: A10995

PI3K Inhibitor

XL147 analogue

XL147 analogue Chemical Structure

CAS NO. 956958-53-5

XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $100.00

Special Price $90.00

25 mg

Regular Price: $200.00

Special Price $180.00

50 mg

Regular Price: $280.00

Special Price $252.00

100 mg

Regular Price: $480.00

Special Price $432.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.
Targets
Target Value
PI3KγIC50: 23nM
PI3KδIC50: 36nM
PI3KαIC50: 39nM
PI3KβIC50: 383nM
DNA-PKIC50: 4.75μM
Vps34IC50: 6.975μM
MEKIC50: >10μM
B-Raf/C-RafIC50: >10μM
mTORIC50: >15μM
In vitro (25°C) DMSO 3 mg/mL (6.68 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.48 mL 222.97 mL
0.5 mM 4.46 mL 22.3 mL 44.59 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10995
Actions Inhibitor
M. Wt 448.5
Formula C21H16N6O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 956958-53-5
Synonyms XL-147, SAR245408
SMILES CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy XL147 analogue | XL147 analogue Supplier | purchase XL147 analogue | XL147 analogue cost | XL147 analogue manufacturer | order XL147 analogue | XL147 analogue distributor | buy 956958-53-5| 956958-53-5 Supplier | purchase 956958-53-5 | 956958-53-5 cost | 956958-53-5 manufacturer | order 956958-53-5 | 956958-53-5 distributor
Rewards