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XL147 analogue


PI3K Inhibitor

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Catalog No. A10995

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
XL147 10mg A10995-10

Regular Price: €95.00

Special Price: €85.50

XL147 25mg A10995-25

Regular Price: €190.00

Special Price: €171.00

XL147 50mg A10995-50

Regular Price: €266.00

Special Price: €239.40

XL147 100mg A10995-100

Regular Price: €456.00

Special Price: €410.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.

XL147 analogue

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Publications citing Adooq Products
XL147 analogue Citations (1)
  • Yushi Hayashida, .et al. Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor, Int J Cancer, 2016, Aug 1;139(3):700-11 PMID: 26989815

Chemical Information

Catalog Num A10995
Actions Inhibitor
M. Wt 448.5
Formula C21H16N6O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 956958-53-5
Synonyms XL-147, SAR245408

Biological Activity

XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.
Target Value
PI3KγIC50: 23nM
PI3KδIC50: 36nM
PI3KαIC50: 39nM
PI3KβIC50: 383nM
DNA-PKIC50: 4.75μM
Vps34IC50: 6.975μM
MEKIC50: >10μM
B-Raf/C-RafIC50: >10μM
mTORIC50: >15μM


Solubility (25°C) * In vitro DMSO 3 mg/mL (6.68 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.48 mL 222.97mL
0.5 mM 4.46 mL 22.3 mL 44.59 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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