XY028-133

Name: XY028-133
Brand: Adooq Bioscience
SKU: A23959
Rating: 5 (288 reviews)

Catalog No.: A23959

PROTAC CDK4/6 Degrader

XY028-133 (Example 14) is a PROTAC-based degrader targeting CDK4/6, composed of ligands for von Hippel-Lindau (VHL) and CDK. It induces selective degradation of CDK4/6 and exhibits anti-tumor activity, making it a useful tool for cell cycle and cancer research.

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XY028-133 2229974-73-4 PROTAC CDK4/6 Degrader

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Grouped product items
Size	Price	Stock
5mg	$315.00	In stock
10mg	$543.00	In stock
50mg	$1,610.00	In stock
100mg	$3,150.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	XY028-133 (Example 14) is a PROTAC-based degrader targeting CDK4/6, composed of ligands for von Hippel-Lindau (VHL) and CDK. It induces selective degradation of CDK4/6 and exhibits anti-tumor activity, making it a useful tool for cell cycle and cancer research.

Product Information

Catalog Num	A23959
Formula	C53H67N11O7S
Molecular Weight	1002.23
CAS Number	2229974-73-4
SMILES	O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCC(N4CCN(C5=CC=C(NC6=NC=C(C(C)=C(C(C)=O)C(N7C8CCCC8)=O)C7=N6)N=C5)CC4)=O)=O)=O)C[C@H](O)C3
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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