YF-2

Name: YF-2
Brand: Adooq Bioscience
SKU: A21018
Rating: 5 (288 reviews)

Catalog No.: A21018

histone acetyltransferase activator

YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease.

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YF-2 1311423-89-8 histone acetyltransferase activator

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Grouped product items
Size	Price	Stock
1mg	$45.00	In stock
5mg	$115.00	In stock
10mg	$190.00	In stock
25mg	$405.00	In stock
50mg	$610.00	In stock
100mg	$870.00	In stock
*10mM 1mL in DMSO**	$125.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description

Targets

Target	Value

Product Information

Catalog Num	A21018
Formula	C20H22ClF3N2O3
Molecular Weight	430.85
CAS Number	1311423-89-8
SMILES	O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C
Synonyms	YF2, YF 2
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	78 mg/mL (181.03 mM)
	Water	78 mg/mL (181.03 mM)
	Ethanol	78 mg/mL (181.03 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.21 mL	116.05 mL	232.1 mL
0.5 mM	4.64 mL	23.21 mL	46.42 mL
1 mM	2.32 mL	11.6 mL	23.21 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

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