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Biological Activity
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells, with IC50 values of 1.0 and 0.57 microM, respectively.
| In vitro | DMSO | 42 mg/mL (116.85 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.82 mL | 139.11 mL | 278.22 mL |
| 0.5 mM | 5.56 mL | 27.82 mL | 55.64 mL |
| 1 mM | 2.78 mL | 13.91 mL | 27.82 mL |
| 5 mM | 0.56 mL | 2.78 mL | 5.56 mL |
*The above data is based on the productmolecular weight 359.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15999 |
|---|---|
| Actions | Antagonist |
| CAS No. | 163769-88-8 |
| Formula | C22H21N3O2 |
| M. Wt | 359.43 |
| Purity | >98% |
| Synonyms | YM 90709, YM90709 |
| SMILES | CC(CC1=CC(OC)=C(OC)C=C12)(C)N3C2=CC4=NC5=CC=CC=C5N=C43 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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