Zapnometinib

Catalog No.: A47981
MEK Inhibitor
Zapnometinib is a potent MEK inhibitor with an IC50 of 5.7 nM, acting primarily on the MAPK/ERK signaling pathway. This compound displays antiviral activity against the influenza virus and possesses antibacterial properties, making it a valuable tool for research applications in virology and microbiology. Its efficacy in inhibiting MEK highlights its potential for studies related to cancer and inflammatory diseases.
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$50.00
In stock
25mg
$60.00
In stock
50mg
$115.00
In stock
100mg
$220.00
In stock
200mg
$310.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZapnometinib is a potent MEK inhibitor with an IC50 of 5.7 nM, acting primarily on the MAPK/ERK signaling pathway. This compound displays antiviral activity against the influenza virus and possesses antibacterial properties, making it a valuable tool for research applications in virology and microbiology. Its efficacy in inhibiting MEK highlights its potential for studies related to cancer and inflammatory diseases.
Product Information
Catalog NumA47981
FormulaC13H7ClF2INO2
Molecular Weight409.55
CAS Number303175-44-2
SMILESO=C(O)C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2Cl
SynonymsPD0184264; ATR-002
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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