Ziconotide

Name: Ziconotide
Brand: Adooq Bioscience
SKU: A66136
Rating: 5 (288 reviews)

Catalog No.: A66136

N-type Calcium Channels Antagonist

Ziconotide is a potent and selective antagonist of N-type calcium channels. By blocking these channels, Ziconotide effectively reduces synaptic transmission and is utilized in chronic pain research. This peptide is an important tool for studying pain mechanisms and the physiological roles of calcium channel modulation in neuronal signaling.

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Ziconotide 107452-89-1 N-type Calcium Channels Antagonist

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Biological Activity

Description	Ziconotide is a potent and selective antagonist of N-type calcium channels. By blocking these channels, Ziconotide effectively reduces synaptic transmission and is utilized in chronic pain research. This peptide is an important tool for studying pain mechanisms and the physiological roles of calcium channel modulation in neuronal signaling.

Product Information

Catalog Num	A66136
Formula	C102H172N36O32S7
Molecular Weight	2639.13
CAS Number	107452-89-1
Sequence shortening	CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 (Disulfide bridge:Cys1-Cys16;Cys8-Cys20;Cys15-Cys25)
SMILES	C([C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@]2(C(=O)N[C@@]3(C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@](CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1)(NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC3)[H])(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N)=O)CSSC2)[H])[H])[H])[H])C4=CC=C(O)C=C4
Synonyms	SNX-111

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