ZLN024 hydrochloride is an allosteric activator of AMP-activated protein kinase (AMPK). It selectively activates various AMPK heterotrimers, including AMPK α1β1γ1, α2β1γ1, α1β2γ1, and α2β2γ1, with EC50 values of 0.42 µM, 0.95 µM, 1.1 µM, and 0.13 µM, respectively. This compound is instrumental in studies related to energy homeostasis, metabolism, and cellular stress response, making it a valuable tool for researchers investigating AMPK-related pathways in various biological contexts.
ZLN024 hydrochloride is an allosteric activator of AMP-activated protein kinase (AMPK). It selectively activates various AMPK heterotrimers, including AMPK α1β1γ1, α2β1γ1, α1β2γ1, and α2β2γ1, with EC50 values of 0.42 µM, 0.95 µM, 1.1 µM, and 0.13 µM, respectively. This compound is instrumental in studies related to energy homeostasis, metabolism, and cellular stress response, making it a valuable tool for researchers investigating AMPK-related pathways in various biological contexts.
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