Home /
JAK / Stat /
JAK /
ZM 39923 HCl

ZM 39923 HCl

Name: ZM 39923 HCl
Brand: Adooq Bioscience
SKU: A13509
Rating: 100 (268 reviews)

Catalog No.: A13509

JAK3 inhibitor

ZM 39923 HCl Chemical Structure

CAS NO. 1021868-92-7

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)

Availability: In stock

Package	Price	Qty
10 mg	$90.00
25 mg	$180.00
50 mg	$300.00
Custom Size	Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Bulk Inquiry

Price Match

Add to Wishlist

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Biological Activity

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)

Targets

TGM2	JAK3	EGFR	JAK1
10 nM	7.1(pIC50)	5.6(pIC50)	4.4(pIC50)

Solubility *

In vitro	DMSO	26 mg/mL (70.67 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (19.02 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.18 mL	135.91 mL	271.81 mL
0.5 mM	5.44 mL	27.18 mL	54.36 mL
1 mM	2.72 mL	13.59 mL	27.18 mL
5 mM	0.54 mL	2.72 mL	5.44 mL

*The above data is based on the productmolecular weight 367.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A13509
Actions	Inhibitor
CAS No.	1021868-92-7
Formula	C23H25NOHCl
M. Wt	367.9
Purity	>98%
Synonyms	JAK3 Inhibitor IV
SMILES	O=C(CCN(CC1=CC=CC=C1)C(C)C)C2=CC3=CC=CC=C3C=C2.Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.