ZM 39923 HCl

Catalog No.: A13509

JAK3 inhibitor

ZM 39923 HCl

ZM 39923 HCl Chemical Structure

CAS NO. 1021868-92-7

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$300.00
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Biological Activity

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)
Targets
TGM2 JAK3 EGFR JAK1
10 nM7.1(pIC50)5.6(pIC50)4.4(pIC50)
In vitro DMSO 26 mg/mL (70.67 mM)
Water Insoluble
Ethanol 7 mg/mL (19.02 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.18 mL 135.91 mL 271.81 mL
0.5 mM 5.44 mL 27.18 mL 54.36 mL
1 mM 2.72 mL 13.59 mL 27.18 mL
5 mM 0.54 mL 2.72 mL 5.44 mL

*The above data is based on the productmolecular weight 367.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13509
Actions Inhibitor
CAS No. 1021868-92-7
Formula C23H25NOHCl
M. Wt 367.9
Purity >98%
Synonyms JAK3 Inhibitor IV
SMILES O=C(CCN(CC1=CC=CC=C1)C(C)C)C2=CC3=CC=CC=C3C=C2.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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