ZM 39923 HCl

Catalog No.: A13509

JAK3 inhibitor

ZM 39923 HCl

ZM 39923 HCl Chemical Structure

CAS NO. 1021868-92-7

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$300.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively)
Targets
TGM2 JAK3 EGFR JAK1
10 nM7.1(pIC50)5.6(pIC50)4.4(pIC50)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.18 mL 135.91 mL 271.81 mL
0.5 mM 5.44 mL 27.18 mL 54.36 mL
1 mM 2.72 mL 13.59 mL 27.18 mL
5 mM 0.54 mL 2.72 mL 5.44 mL

*The above data is based on the productmolecular weight 367.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13509
Actions Inhibitor
M. Wt 367.9
Formula C23H25NOHCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1021868-92-7
Synonyms JAK3 Inhibitor IV
SMILES O=C(CCN(CC1=CC=CC=C1)C(C)C)C2=CC3=CC=CC=C3C=C2.Cl

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