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Biological Activity
ZM39923 is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.17 mL | 150.85 mL | 301.7 mL |
| 0.5 mM | 6.03 mL | 30.17 mL | 60.34 mL |
| 1 mM | 3.02 mL | 15.09 mL | 30.17 mL |
| 5 mM | 0.6 mL | 3.02 mL | 6.03 mL |
*The above data is based on the productmolecular weight 331.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16227 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 273727-89-2 |
| Formula | C23H25NO |
| M. Wt | 331.45 |
| Purity | >98% |
| Synonyms | ZM-39923 |
| SMILES | CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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