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ZM39923

JAK1/3 inhibitor

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Catalog No. A16227

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ZM39923 10mg A16227-10
$80.00
ZM39923 50mg A16227-50
$280.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ZM39923 is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

ZM39923

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Chemical Information

Catalog Num A16227
Actions Inhibitor
M. Wt 331.45
Formula C23H25NO
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 273727-89-2
Synonyms ZM-39923
SMILES CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3
Chemical Name 3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one

Biological Activity

Description
ZM39923 is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.17 mL 150.85 mL 301.7mL
0.5 mM 6.03 mL 30.17 mL 60.34 mL
1 mM 3.02 mL 15.09 mL 30.17 mL
5 mM 0.6 mL 3.02 mL 6.03 mL

*The above data is based on the productmolecular weight 331.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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