(-)-Zuonin A is a selective inhibitor of c-Jun N-terminal kinases (JNKs), demonstrating IC50 values of 1.7 μM, 2.9 μM, and 1.74 μM for JNK1, JNK2, and JNK3, respectively. As a naturally occurring lignin, it exhibits potent inhibitory activity, making it a valuable reagent for studies investigating JNK signaling pathways. This compound is applicable in research areas including cancer biology, neuroprotection, and inflammation.
(-)-Zuonin A is a selective inhibitor of c-Jun N-terminal kinases (JNKs), demonstrating IC50 values of 1.7 μM, 2.9 μM, and 1.74 μM for JNK1, JNK2, and JNK3, respectively. As a naturally occurring lignin, it exhibits potent inhibitory activity, making it a valuable reagent for studies investigating JNK signaling pathways. This compound is applicable in research areas including cancer biology, neuroprotection, and inflammation.
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