ZXH-3-26

Catalog No.: A18399

PROTAC BRD4 degrader

ZXH-3-26

ZXH-3-26 Chemical Structure

CAS NO. 2243076-67-5

ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM.

Availability: In stock

Package Price Qty
5 mg
$280.00
10 mg
$520.00
50 mg
$1,780.00
100 mg
$2,680.00
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Biological Activity

ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.73 mL 63.67 mL 127.34 mL
0.5 mM 2.55 mL 12.73 mL 25.47 mL
1 mM 1.27 mL 6.37 mL 12.73 mL
5 mM 0.25 mL 1.27 mL 2.55 mL

*The above data is based on the productmolecular weight 785.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18399
Actions Degrader
M. Wt 785.27
Formula C38H37ClN8O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2243076-67-5
Synonyms ZXH326, ZXH-326
SMILES O=C(OC)C[[email protected]]1C2=NN=C(C)N2C3=C(C(C)=C(C(NCCCCCNC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)S3)C(C7=CC=C(Cl)C=C7)=N1

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