Apigenin

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Protein kinase inhibitor

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Catalog No. A10081

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Apigenin 50mg A10081-50

Regular Price: $60.00

Special Price: $51.00

Apigenin 100mg A10081-100

Regular Price: $100.00

Special Price: $85.00

Apigenin 200mg A10081-200

Regular Price: $180.00

Special Price: $153.00

Apigenin 10mM * 1mL in DMSO A10081-10mM-D

Regular Price: $62.00

Special Price: $52.70

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Apigenin, found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally-occurring glycosides. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. Apigenin is a ligand for central benzodiazepine receptors that competitively inhibited the binding of flunitrazepam with a Ki of 4μM, exerting anxiolytic and slight sedative effects.

Apigenin

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Chemical Information

Catalog Num A10081
Actions Inhibitor
M. Wt 270.2
Formula C15H10O5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 520-36-5
Synonyms 4’,5,7-trihydroxyflavone
SMILES code C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
Chemical Name 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Biological Activity

Description

Apigenin, found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally-occurring glycosides. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. Apigenin is a ligand for central benzodiazepine receptors that competitively inhibited the binding of flunitrazepam with a Ki of 4μM, exerting anxiolytic and slight sedative effects.

Targets
CYP2C9
2 μM(Ki)

Solubility

Solubility (25°C)* In vitro DMSO 54 mg/mL (199.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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