MRK 560

Catalog No.: A15304
γ-secretase inhibitor
MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.
Grouped product items
Product Name Price Stock Qty
MRK 560 10mg
$170.00
In stock
MRK 560 50mg
$760.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.
Targets
Target Value
Product Information
Catalog Num A15304
Formula C19H17ClF5NO4S2
Molecular Weight 517.92
CAS Number 677772-84-8
SMILES C1CC(CCC1NS(=O)(=O)C(F)(F)F)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
Synonyms MRK-560, MRK560
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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