MRK 560

γ-secretase inhibitor

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Catalog No. A15304

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MRK 560 10mg A15304-10
$170.00
MRK 560 50mg A15304-50
$760.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.

MRK 560

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Chemical Information

Catalog Num A15304
Actions Inhibitor
M. Wt 517.92
Formula C19H17ClF5NO4S2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 677772-84-8
Synonyms MRK-560, MRK560
SMILES code C1CC(CCC1NS(=O)(=O)C(F)(F)F)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
Chemical Name N-((1r,4r)-4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)-1,1,1-trifluoromethanesulfonamide

Biological Activity

Description
MRK 560 is an orally bioavailable gamma-secretase inhibitor with the ability to markedly reduce Abeta peptide in the brain and CSF of the rat and confirm the utility of the rat for assessing the effects of gamma-secretase inhibitors on central nervous system Abeta(40) levels in vivo.

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