Fig. 1 · Structure

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17-trifluoromethylphenyl trinor Prostaglandin F2α

Prostaglandin Receptor

17-Trifluoromethylphenyl trinor Prostaglandin F2α is a potent agonist of the prostaglandin FP receptor, known for its significant biological activity as a luteolytic agent. This compound features a trifluoromethyl-substituted aromatic ring structure, akin to the phenoxy ring of travoprost, contributing to its efficacy in lowering intraocular pressure. Its pharmacological profile suggests potential applications in the treatment of glaucoma and other conditions where modulation of prostaglandin pathways is beneficial. Its luteolytic potency is comparable to or surpasses that of established agents such as fluprostenol and cloprostenol.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 221246-34-0
Applications Prostaglandin Receptor
Formula C24H31F3O5
Molecular Weight 456.50
Synonyms 17-Trifluoromethylphenyl trinor PGF2α
SMILES
O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](CCC2=CC(C(F)(F)F)=CC=C2)O)C/C=C\CCCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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