18α-Glycyrrhetinic acid

Catalog No.: A12199

The aglycone of glycyrrhizin

18α-Glycyrrhetinic acid

18α-Glycyrrhetinic acid Chemical Structure

CAS NO. 1449-05-4

18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1).

Availability: In stock

Package Price Qty
5 mg
$180.00
10 mg
$320.00
50 mg
$1,200.00
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Biological Activity

18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1).
In vitro DMSO 85 mg/mL (180.59 mM)
Water Insoluble
Ethanol 41 mg/mL (87.11 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.23 mL 212.46 mL
0.5 mM 4.25 mL 21.25 mL 42.49 mL
1 mM 2.12 mL 10.62 mL 21.25 mL
5 mM 0.42 mL 2.12 mL 4.25 mL

*The above data is based on the productmolecular weight 470.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12199
CAS No. 1449-05-4
Formula C30H46O4
M. Wt 470.68
Purity >98%
Synonyms 18α-GA
SMILES C[[email protected]]12CC[[email protected]](C[[email protected]@H]1C3=CC(=O)C4[[email protected]]5(CC[[email protected]@H](C([[email protected]@H]5CC[[email protected]]4([[email protected]@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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