18α-Glycyrrhetinic acid

Name: 18α-Glycyrrhetinic acid
SKU: A12199
Price: 144 USD
Rating: 5 (288 reviews)

Catalog No.: A12199

NF-kB inhibitor/Proteasome activator

18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1).

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Grouped product items
Product Name	Price	Stock
18α-Glycyrrhetinic acid 5mg	Special Price $144.00 Regular Price $180.00	In stock
18α-Glycyrrhetinic acid 10mg	Special Price $256.00 Regular Price $320.00	In stock
18α-Glycyrrhetinic acid 50mg	Special Price $960.00 Regular Price $1,200.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription

18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice. It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1).

Targets

Target	Value

Product Information

Catalog Num	A12199
Formula	C30H46O4
Molecular Weight	470.68
CAS Number	1449-05-4
SMILES	C[C@]12CC[C@](C[C@@H]1C3=CC(=O)C4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O
Synonyms	18α-GA
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	85 mg/mL (180.59 mM)
	Water	Insoluble
	Ethanol	41 mg/mL (87.11 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.25 mL	106.23 mL	212.46 mL
0.5 mM	4.25 mL	21.25 mL	42.49 mL
1 mM	2.12 mL	10.62 mL	21.25 mL
5 mM	0.42 mL	2.12 mL	4.25 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂