2,4-Di-tert-butylphenol (2,4-DTBP) is a potent RXRα activator and a ligand for human estrogen receptors, exhibiting significant anti-inflammatory and antioxidant properties. This compound has the capacity to induce apoptosis in tumor cells and can activate various RXRα-associated pathways, including LXRα/RXRα and PPARγ/RXRα. Additionally, 2,4-DTBP demonstrates antiviral and antifungal activities while also showing potential to mitigate Aβ-induced neurotoxicity. It serves as a valuable intermediate for synthesizing antioxidants, UV stabilizers, and is utilized in pharmaceutical and fragrance manufacturing.
2,4-Di-tert-butylphenol (2,4-DTBP) is a potent RXRα activator and a ligand for human estrogen receptors, exhibiting significant anti-inflammatory and antioxidant properties. This compound has the capacity to induce apoptosis in tumor cells and can activate various RXRα-associated pathways, including LXRα/RXRα and PPARγ/RXRα. Additionally, 2,4-DTBP demonstrates antiviral and antifungal activities while also showing potential to mitigate Aβ-induced neurotoxicity. It serves as a valuable intermediate for synthesizing antioxidants, UV stabilizers, and is utilized in pharmaceutical and fragrance manufacturing.
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