2-Deethoxy-2-hydroxyphantomolin

Catalog No.: A27663
Antifungal/Antibacterial Agent
2-Deethoxy-2-hydroxyphantomolin is a germacranolide known for its antifungal and antibacterial properties. Isolated from the whole plant of Elephantopus tomentosus and leaves of E. mollis, it exhibits moderate activity against Candida albicans, with a clearing zone of 14 mm, and slight activity against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis (12-14 mm clearing zones). Additionally, it shows some efficacy against Trichophyton mentagrophytes, making it a compound of interest for research in microbial infections.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2-Deethoxy-2-hydroxyphantomolin is a germacranolide known for its antifungal and antibacterial properties. Isolated from the whole plant of Elephantopus tomentosus and leaves of E. mollis, it exhibits moderate activity against Candida albicans, with a clearing zone of 14 mm, and slight activity against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis (12-14 mm clearing zones). Additionally, it shows some efficacy against Trichophyton mentagrophytes, making it a compound of interest for research in microbial infections.
Product Information
Catalog NumA27663
FormulaC19H22O6
Molecular Weight346.37
CAS Number821799-76-2
SMILESCC(C(O[C@@H]1[C@]2([H])[C@@](OC(C2=C)=O)([H])[C@@]3([H])O[C@](C=C3C)(/C=C(C1)/C)O)=O)=C
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