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2-Hydroxyaclacinomycin B

Catalog No.: A50312
Antibiotic
2-Hydroxyaclacinomycin B is an anthracycline antibiotic known for its ability to inhibit RNA synthesis. Isolated from Streptomyces galilaeus A-862 (FERM BP-45), this compound exhibits significant anti-tumor activity. It serves as a valuable tool in cancer research, enabling studies focused on mechanisms of action and therapeutic potential within oncology.
2-Hydroxyaclacinomycin B 85819-82-5 Antibiotic
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description2-Hydroxyaclacinomycin B is an anthracycline antibiotic known for its ability to inhibit RNA synthesis. Isolated from Streptomyces galilaeus A-862 (FERM BP-45), this compound exhibits significant anti-tumor activity. It serves as a valuable tool in cancer research, enabling studies focused on mechanisms of action and therapeutic potential within oncology.
Product Information
Catalog NumA50312
FormulaC42H51NO16
Molecular Weight825.85
CAS Number85819-82-5
SMILESO=C1C2=C(C(O)=CC(O)=C2)C(C3=C1C=C(C4=C3O)[C@@H](C(OC)=O)[C@@](O)(CC)C[C@@H]4O[C@@H]5O[C@H]([C@H]([C@H](C5)N(C)C)O[C@@H]6O[C@H]([C@H]7O[C@H](OC(C(C8)=O)C)[C@H]8O[C@H]7C6)C)C)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Microbiology > Antifection > Antibiotic