Catalog No.
Product Name
Application
Product Information
Citations
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Glycopeptide Antibiotic
Bleomycin is a glycopeptide antibiotic produced by the bacterium Streptomyces verticillus. It acts by induction of DNA strand breaks.- Ou QX, .et al. , Bioelectrochemistry, 2017, Jun;115:47-55 PMID: 28063751
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Antibiotic
Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.- Seungmo Kim, .et al. , Tuberculosis, 2025, 152: 102630 PMID: 40120193
- Thanh Quang Nguyen, .et al. , Antimicrob Agents Chemother, 2022, Dec 20;66(12):e0044822 PMID: 36321819
- Meikle V, .et al. , Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480
- World Health Organization, .et al. , World Health Organization, 2018, WHO/CDS/TB/2018.24
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antibiotic
Cefoxitin Sodium is a semisynthetic cephamycin antibiotic resistant to beta-lactamase. It is derived from Cephamycin C and is highly resistance to β-lactamase inactivation.- Viktoria Lazar, .et al. , Nature, 2022, 610: 540-546 PMID: 36198788
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broad-spectrum antibiotic
Tobramycin Sulfate is a broad-spectrum antibiotic. It is effective against gram-negative bacteria, and especially potent against the Pseudomonas species.- Viktoria Lazar, .et al. , Nature, 2022, 610: 540-546 PMID: 36198788
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Fluoroquinolone antibiotic
ABT-492 is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens. -
nitroimidazole antibiotic medication
Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. -
Antibiotic
Berberine hemisulfate is an alkaloid with antibiotic properties derived from the traditional Chinese herbal medicine Huanglian. It demonstrates significant antimicrobial activity and possesses anti-inflammatory, antitumor, cardiovascular protective, and neuroprotective effects. This compound is valuable for research applications exploring infections, immune response modulation, and potential therapeutic avenues for various diseases. -
Antibiotic
Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases. -
Antibiotic
Erythromycin is a macrolide antibiotic that targets bacterial 50S ribosomal subunits, effectively inhibiting RNA-dependent protein synthesis by obstructing transpeptidation and translocation reactions. This compound demonstrates a broad spectrum of antimicrobial activity against various bacteria, making it valuable in microbiological research. Additionally, erythromycin has been shown to possess antitumor and neuroprotective properties, contributing to its usefulness in diverse areas of biomedical research. -
Antibiotic
Tetracycline is a broad-spectrum antibiotic that targets bacterial protein synthesis by binding to the 30S ribosomal subunit, inhibiting translation. It demonstrates activity against a diverse array of microorganisms, including gram-positive and gram-negative bacteria, as well as chlamydiae, mycoplasmas, and rickettsiae. This compound is widely utilized in research related to bacterial infections and antibiotic resistance mechanisms. -
Antibiotic
Acetoxycycloheximide is an antibiotic with potent antitumor properties, primarily functioning as a protein synthesis inhibitor. It effectively induces procaspase-3 activation, leading to apoptosis through the release of cytochrome c from mitochondria via the JNK signaling pathway. Additionally, acetoxycycloheximide downregulates cell surface TNF-R1 by activating the ERK and p38 MAPK pathways, thereby inhibiting TNF-α-mediated NF-κB signaling. This reagent is valuable for research related to inflammatory and immune diseases as well as cancer. -
Antibiotic
Metronidazole hydrochloride is a nitroimidazole antibiotic with a primary mechanism of action against anaerobic bacteria. It is effective in the treatment of various anaerobic infections and possesses the ability to penetrate the blood-brain barrier. Research applications include studying its effects on inflammation and skeletal muscle contraction associated with long-term use. -
Polyether Antibiotic
Monensin, a polyether antibiotic, functions primarily as an ionophore that mediates Na+/H+ exchange. It has been identified as a potent inhibitor of Wnt signaling, leading to significant enlargement of multivesicular bodies (MVBs) and modulating exosome secretion. This compound is utilized in research focused on bacterial, fungal, and parasitic infections, and it also exhibits anticancer properties, making it a valuable tool in various biological studies. -
Antibiotic/FOXM1 Inhibitor
Siomycin A is a thiopeptide antibiotic that selectively inhibits Forkhead box M1 (FOXM1), while sparing other Forkhead box family members. It exhibits significant anti-tumor activity and promotes apoptosis, making it a valuable tool for cancer research. This compound is particularly useful for studies focused on the role of FOXM1 in tumorigenesis and therapeutic resistance. -
Antibiotic
Terrein is an antibiotic that functions as a melanogenesis inhibitor. It induces apoptosis in breast cancer cell lines and acts as an inhibitor of quorum sensing and cyclic di-GMP levels in Pseudomonas aeruginosa. This compound is valuable in studying mechanisms of cancer cell regulation and bacterial communication processes. -
Antibiotic/DNA Inhibitor
Bleomycin A5 (hydrochloride) is a glycopeptide antibiotic that primarily functions as a DNA inhibitor. This compound exerts its cytotoxic effects by chelating Fe2+, which leads to the formation of reactive species that induce both single-strand and double-strand breaks in DNA, thereby disrupting DNA replication. Additionally, Bleomycin A5 (hydrochloride) inhibits Drp1-mediated mitochondrial fission and modulates the PINK1/Parkin pathway, contributing to mitochondria-mediated apoptosis. It is widely utilized in cancer research applications. -
Antibiotic and APN Inhibitor
Actinonin is a naturally occurring antibiotic that functions primarily as an aminopeptidase N inhibitor. It exhibits potent antimicrobial activity and acts as a reversible peptide deformylase (PDF) inhibitor with a Ki value of 0.28 nM. Additionally, Actinonin shows inhibitory effects on matrix metalloproteinases MMP-1, MMP-3, MMP-8, and MMP-9, with respective Ki values of 300 nM, 1,700 nM, 190 nM, and 330 nM. It also possesses pro-apoptotic properties and has demonstrated antiproliferative and antitumor activities, making it a valuable tool for cancer research and therapeutic exploration. -
Antibiotic
Bleomycin A5 is a glycopeptide antibiotic that exerts cytotoxic effects primarily through its interaction with Fe2+, leading to the formation of a complex that induces both single-strand and double-strand DNA breaks, while inhibiting DNA replication. Additionally, it targets Drp1-mediated mitochondrial fission and suppresses the PINK1/Parkin pathway-mediated mitophagy, ultimately promoting mitochondria-mediated cellular apoptosis. This compound is valuable in cancer research, particularly in studies focused on mechanisms of apoptosis and DNA damage responses. -
Antibiotic
Chrysomycin A is an antibiotic derived from the Streptomyces genus. It demonstrates significant antitumor properties, alongside effective activity against Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus (MRSA). In glioblastoma research, Chrysomycin A has been shown to inhibit cancer cell proliferation, migration, and invasion by targeting the Akt/GSK-3β/β-catenin signaling pathway, making it a valuable tool for cancer studies and antibiotic research. -
Antibiotic
Ceftiofur sodium is an antibiotic that acts as a cell wall synthesis inhibitor by targeting bacterial penicillin-binding proteins (PBPs). It exhibits bactericidal activity through the inhibition of peptidoglycan synthesis, resulting in bacterial cell lysis. Additionally, Ceftiofur sodium has anti-inflammatory properties by inhibiting the activation of NF-κB and MAPKs, which decreases the secretion of pro-inflammatory cytokines including TNF-α, IL-1β, and IL-6. This compound is applicable in research related to antibiotic resistance and inflammatory responses. -
Antibiotic
Cefaclor monohydrate is an orally active cephalosporin antibiotic that targets penicillin-binding protein 3 (PBP3). It is effective against a variety of bacterial infections, including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections. Additionally, Cefaclor has potential applications in research related to depression and other bacterial pathologies. -
Antibiotic
Erythromycin Ethylsuccinate is an antibiotic that primarily targets bacterial infections by inhibiting protein synthesis in susceptible microorganisms. It demonstrates an antimicrobial spectrum that is comparable to, or slightly broader than, that of penicillin, making it effective against a variety of Gram-positive and some Gram-negative bacteria. Additionally, Erythromycin Ethylsuccinate exhibits antiviral activity against HIV-1, providing a versatile option for researchers studying bacterial and viral pathogens. Its applications include exploring antimicrobial resistance and developing new therapeutic strategies. -
Antibiotic
Oxolinic acid is an antibiotic effective against both Gram-negative and Gram-positive bacteria. It is primarily utilized in research focused on acute and chronic urinary tract infections. Additionally, Oxolinic acid functions as a DNA/RNA synthesis inhibitor and acts as a dopamine uptake inhibitor, demonstrating stimulatory effects on locomotor activity in murine models. -
Antibiotic
Pefloxacin mesylate dihydrate is a broad-spectrum antibiotic that primarily inhibits DNA gyrase, disrupting DNA replication. This compound demonstrates significant antibacterial activity against both Escherichia coli and Pseudomonas aeruginosa, with MIC90 values of 0.12 mg/L and 4 mg/L, respectively, and also targets Bacteroides fragilis with an MIC90 of 16 mg/L. Additionally, Pefloxacin mesylate dihydrate exhibits anti-Plasmodium yoelii activity and can enhance UVA-induced edema and immunosuppression. Its diverse profile makes it a valuable tool for infection studies and related research applications. -
Antibiotic
Succinylsulfathiazole is a sulfonamide antibiotic that targets bacterial folate synthesis, providing localized, gut-specific antibacterial activity. This compound effectively reduces coliform counts, suppresses intestinal bacterial growth, and depletes gut folate-producing bacteria while modulating hepatic mTOR signaling. Succinylsulfathiazole is utilized in research focused on nutrient deficiency and its implications, as it induces folate deficiency and related nutritional symptoms in animal models such as rats and C57BL/6 mice. This antibiotic is valuable for understanding the mechanisms of gut flora modulation and the impact on nutritional status. -
Ansamycin Antibiotic
Rifamycin sodium is an orally active ansamycin antibiotic that inhibits DNA-dependent RNA synthesis. It demonstrates significant antibacterial activity against Mycobacterium tuberculosis and modulates hepatic bile acid metabolism. Additionally, Rifamycin sodium exhibits anti-inflammatory properties, making it valuable for studying Mycobacterium tuberculosis, Bacteroides fragilis infections, and inflammation induced by lipopolysaccharides. -
Antibiotic
Erythromycin thiocyanate is a macrolide antibiotic that targets bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively inhibiting RNA-dependent protein synthesis through interference with transpeptidation and translocation processes. This compound exhibits broad-spectrum antimicrobial activity, making it valuable in research applications related to bacterial infections. Additionally, erythromycin thiocyanate has been shown to possess antitumor and neuroprotective properties, expanding its potential utility across various biomedical research fields. -
Quinolone Antibiotic
Lomefloxacin is a difluoroquinolone antibiotic that primarily targets bacterial topoisomerase II, inhibiting DNA supercoiling and replication. This compound exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria and is effective in inducing reactive oxygen species (ROS) production and apoptosis. Additionally, Lomefloxacin demonstrates promising anticancer efficacy against melanoma, making it a valuable tool for research applications involving systemic bacterial infections and skin cancer studies. -
Antibiotic
Bafilomycin C1 is a macrolide antibiotic that functions as a specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). It exhibits potent antibacterial and antifungal activity, particularly against gram-positive organisms. Additionally, Bafilomycin C1 has been shown to induce apoptosis, making it a valuable tool for research into hepatocellular carcinoma (HCC) and related cellular processes. -
Antibiotic
Roridin E is an antibiotic that exhibits cell-inhibiting and fungicidal properties. It is known for its efficacy in combating various fungal infections and serves as a valuable tool in antimicrobial research. Roridin E's mechanism of action, which involves disrupting cellular processes in target organisms, makes it suitable for studies aimed at understanding fungal pathogenesis and potential therapeutic interventions. -
Antifungal Antibiotic Agent
Candicidin is a polyene antifungal antibiotic agent that functions by binding to ergosterol in fungal cell membranes, leading to increased permeability and cell death. It exhibits potent antifungal activity against a range of pathogenic fungi. Candicidin is primarily used in research applications focused on fungal infections and the mechanisms of antifungal resistance. -
Antibiotic
Polyhexamethyleneguanidine hydrochloride is a cationic polymer known for its broad-spectrum antimicrobial activity. It primarily exerts its antibacterial effects by interacting with bacterial and fungal cell membranes, leading to disruption of membrane integrity. This compound is valuable in research related to disinfection, water treatment, and agricultural pesticides. -
Antibiotic
Pyrrolnitrin is an antibiotic derived from Pseudomonas pyrrocinia, demonstrating potent activity against a wide range of fungal pathogens, yeast, and gram-positive bacteria. This compound is utilized extensively in research to explore antimicrobial mechanisms and develop therapeutic strategies against resistant infections. Its broad-spectrum effectiveness makes it a valuable tool in microbiological studies and antibiotic susceptibility testing. -
Antibiotic
Piperlonguminine is an alkaloid amide derived from Piper species, exhibiting significant antibacterial properties. Furthermore, it demonstrates a range of biological activities, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, and antifungal effects. This compound is of interest in various research applications, particularly in the fields of pharmaceutical development and disease prevention. -
Antibiotic Agent
Tyrothricin is a polypeptide antibiotic mixture derived from Bacillus brevis, comprising tyrocidines and gramicidins. This compound exhibits broad-spectrum antimicrobial activity, effectively targeting bacteria, fungi, and some viruses. Tyrothricin is commonly used in formulations for the treatment of sore throat and the healing of infected superficial and small-area wounds, making it valuable in both clinical and research settings. -
Antibiotic
α-Terpineol is an antimicrobial compound primarily targeting periodontopathic and cariogenic bacteria. This compound demonstrates significant antifungal activity against Trichophyton mentagrophytes, potentially causing irreversible cellular damage. Additionally, α-Terpineol exhibits antineuropathic and anti-inflammatory properties, making it a valuable reagent for research involving diarrhea, neuropathic pain, infections, and inflammation. -
Antibiotic
Antibiotic WB is an antibacterial agent with notable antifungal properties, derived from the soil fungus strain 38. This compound exhibits strong inhibitory effects on various pathogenic microorganisms, making it a valuable tool for research in infection control and microbial resistance studies. Its applications extend to evaluating antifungal efficacy and exploring mechanisms of action against resistant strains. -
Antibiotic
Alisamycin is an antibiotic belonging to the manumycin group, primarily targeting Gram-positive bacteria and certain fungi. It exhibits antimicrobial activity and possesses weak antitumor properties, making it useful in various research applications, including studies on bacterial resistance mechanisms and the exploration of its potential therapeutic effects. This compound is valuable for investigations into antibiotic efficacy and the biological pathways underlying its action. -
Antibiotic
Herbarin is a quinone antibiotic that exhibits broad-spectrum antimicrobial activity. It demonstrates effectiveness against Gram-positive and Gram-negative bacteria, as well as the pathogen responsible for Citrus Canker and the fungal pathogen causing potato early blight. Herbarin also shows inhibitory effects on Aspergillus niger and several other fungi, making it a valuable tool for studying bacterial and fungal infections in agricultural and clinical research applications. -
Antibiotic
Kinamycin B is an antibiotic derived from Streptomyces murayamaensis, primarily targeting fungal pathogens. This compound demonstrates significant antifungal activity, making it a valuable tool for research in microbial resistance and infectious disease studies. Its application extends to exploring the mechanisms of action in antifungal treatments and assessing potential therapeutic developments. -
Antibiotic
Pradimicin Q is an antibiotic that targets bacterial cell membranes. It exhibits cytotoxic effects against human colon HCT-116 cells and murine melanoma B16-F10 cells with IC50 values of 75 μg/mL and 100 μg/mL, respectively. This compound is primarily utilized in research applications focusing on antimicrobial activity and the study of cancer cell response to antibiotic treatment. -
Antibiotic
(E/Z)-Tapinarof (3,5-dihydroxy-4-isopropylstilbene) is a broad-spectrum antibiotic that targets various microbial pathogens. Exhibiting significant antibacterial, antifungal, and anti-nematode activities, (E/Z)-Tapinarof is valuable for research in infectious disease and antibiotic resistance studies. Its diverse biological profile makes it a useful tool for exploring therapeutic strategies against a range of microbial infections. -
Antibiotic
Ezomycin A2 is an antifungal antibiotic that targets various phytopathogens. It exhibits significant activity against Sclerotinia sclerotiorum and Botrytis, effectively controlling infections caused by these pathogens, as well as offering protection against candidiasis in crops. Its biological activity makes it a valuable reagent for research applications in plant disease management and crop protection studies. -
Antibiotic
Polyoxin G is a nucleoside antifungal antibiotic that primarily targets chitin synthase in fungal cells. It exhibits potent activity against various fungal pathogens, particularly in the management of rice sheath blight. This compound is utilized in agricultural research to develop novel strategies for controlling fungal diseases in crops. -
Antifungal Antibiotic
Pradimicin T1 is an antifungal antibiotic that targets a wide range of filamentous fungi and yeast-like fungi. It exhibits potent antifungal activity, making it a valuable tool in the study of fungal infections and the development of antifungal therapies. Pradimicin T1 is commonly utilized in research applications focusing on fungal biology and mechanisms of resistance. -
Antibiotic
Malonylniphimycin is a macrolide antibiotic that targets Gram-positive bacteria, fungi, and yeasts. Isolated from Streptomyces strain hygroscopicus B-7, it demonstrates potent antibacterial activity that makes it a valuable tool for research in antimicrobial resistance and the development of new therapeutic strategies. Its unique structural features and resistance profile provide insights into the mechanisms of action and efficacy against various pathogens. -
Antibiotic
Nanaomycin B is an antibiotic that exerts its activity against Gram-positive bacteria, mycobacteria, mycoplasma, and fungi. This compound is utilized in biological research for its potent antimicrobial properties and its ability to inhibit the growth of various microorganisms. Nanaomycin B serves as a valuable tool in studies involving antibiotic resistance and microbial pathogenesis. -
Antibiotic
Ezomycin D2 is an antifungal antibiotic that targets phytopathogens. It demonstrates significant activity against Sclerotinia sclerotiorum and Botrytis, offering effective control against these fungi as well as Candidiasis in crop settings. This compound is valuable for researchers studying agricultural disease management and developing sustainable solutions for crop protection. -
Antibiotic
Polyoxin L is a nucleoside antifungal antibiotic that targets the biosynthesis of chitin in fungal cell walls. It exhibits potent antifungal activity, particularly against rice sheath blight, making it valuable for agricultural research. This compound is useful in studies aimed at understanding fungal resistance mechanisms and developing effective plant protection strategies.
