Catalog No.
Product Name
Application
Product Information
Citations
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Glycopeptide Antibiotic
Bleomycin is a glycopeptide antibiotic produced by the bacterium Streptomyces verticillus. It acts by induction of DNA strand breaks.- Ou QX, .et al. , Bioelectrochemistry, 2017, Jun;115:47-55 PMID: 28063751
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Antibiotic
Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.- Seungmo Kim, .et al. , Tuberculosis, 2025, 152: 102630 PMID: 40120193
- Thanh Quang Nguyen, .et al. , Antimicrob Agents Chemother, 2022, Dec 20;66(12):e0044822 PMID: 36321819
- Meikle V, .et al. , Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480
- World Health Organization, .et al. , World Health Organization, 2018, WHO/CDS/TB/2018.24
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antibiotic
Cefoxitin Sodium is a semisynthetic cephamycin antibiotic resistant to beta-lactamase. It is derived from Cephamycin C and is highly resistance to β-lactamase inactivation.- Viktoria Lazar, .et al. , Nature, 2022, 610: 540-546 PMID: 36198788
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broad-spectrum antibiotic
Tobramycin Sulfate is a broad-spectrum antibiotic. It is effective against gram-negative bacteria, and especially potent against the Pseudomonas species.- Viktoria Lazar, .et al. , Nature, 2022, 610: 540-546 PMID: 36198788
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natural cyclic oligopeptide antibiotic
Antibiotic that inhibits bacterial protein synthesis. Inhibits mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery and the activity of initiation factor 2 (IF-2). Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression. -
Broad-spectrum antibiotic
Cefadroxil, also known as Duricef, is an antibiotic effective against pyodermic skin diseases, such as Staphylococcus aureus and Streptococcus pyogenes. -
cephalosporin antibiotic
Cefuroxime axetil is a second generation cephalosporin antibiotic with a broad spectrum activity against Gram positive and Gram negative bacteria. -
Antibiotic
Ceforanide is a semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. -
antibiotic
Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas -
broad-spectrum antibiotic
Amoxicillin Trihydrate is a broad-spectrum antibiotic. It binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Inactivated PBP interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. -
Antibiotics
Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively. -
Antibiotic
Sulbenicillin disodium is a semisynthetic penicillin-type antibiotic. -
antibiotic
Pivmecillinam hydrochloride is active against gram-negative organisms and used as for amdinocillin. Pivmecillinam is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic. -
semisynthetic antibiotic
Penicillin G procaine is a semisynthetic antibiotic prepared by combining penicillin G with Procaine. -
macrolide antibiotic
Erythromycin estolate is a macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. -
antibiotics
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. -
antibiotic
Ceftriaxone sodium is an antibiotic, a third-generation cephalosporin. Like other third-generation cephalosporins, it has broad-spectrum activity against Gram-positive bacteria and expanded Gram-negative coverage compared to second-generation agents. -
semisynthetic antibiotic
Penicillin G benzathine anhydrous is a semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine. -
broad-spectrum penicillin antibiotic
Penicillin V potassium is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms. -
broad spectrum antibiotic
Chlorhexidine digluconate solution is a bis-biguanide family cationic broad spectrum antibiotic. Studies indicate that chlorhexidine digluconate solution functions, via destabilization of the outer bacterial membrane, which resulted in the release of periplasmic enzymes in gram negative bacteria. -
Antibiotic
Sulfaquinoxaline sodium salt is an antibiotic which has activity against a broad spectrum of Gram-negative and Gram-positive bacteria. -
Antibiotic
Robenidine hydrochloride is an antibiotic used for the control of coccidiosis, a debilitating protozoal infection in poultry. -
Antibiotic
Rifalazil, a rifamycin derivative, targets bacterial DNA-dependent RNA polymerase, specifically inhibiting the β-subunit to disrupt RNA synthesis and induce bacterial cell death. This antibiotic demonstrates exceptional potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, Chlamydia pneumoniae, and Chlamydia trachomatis, with MIC values ranging from 0.00025 to 0.0025 μg/ml. Rifalazil shows promising potential for applications in treating Chlamydia infections, Clostridium difficile-associated diarrhea (CDAD), and tuberculosis (TB). -
Antibiotic
Phleomycin is a copper-dependent antibiotic known for its DNA-damaging properties. It exerts its biological activity by binding to DNA and generating reactive oxygen species (ROS) in the presence of reducing agents, leading to both single-strand and double-strand breaks. This compound is extensively utilized in cancer research, microbial genetic transformation, serving as a screening marker to enhance fungal transformation efficiency, and the study of DNA repair mechanisms. -
Quinolone Antibiotic
Danofloxacin is a quinolone antibiotic that primarily targets bacterial DNA gyrase, leading to the inhibition of DNA replication and transcription. This mechanism disrupts the growth and proliferation of bacteria. Danofloxacin is effective against a range of bacterial infections, including those caused by Escherichia coli, Mycoplasma, and other pathogenic organisms, making it a valuable tool for related research applications. -
Macrolide Antibiotic
Erythromycin lactobionate is a macrolide antibiotic that targets bacterial 50S ribosomal subunits, inhibiting RNA-dependent protein synthesis through obstruction of transpeptidation and/or translocation processes. This compound demonstrates a broad spectrum of antimicrobial activity, making it valuable for various bacterial infections. Additionally, erythromycin lactobionate has shown potential antitumor and neuroprotective effects, presenting opportunities for research in oncology and neurobiology. -
Antibiotic
Pefloxacin is a broad-spectrum antibiotic that targets DNA gyrase, effectively inhibiting DNA replication. It exhibits significant antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis, with MIC90 values of 0.12, 4, and 16 mg/L, respectively. In addition to its antibacterial properties, Pefloxacin has demonstrated efficacy in reducing Plasmodium yoelii infections and may enhance UVA-induced edema and immunosuppression. This compound is suitable for various infection-related research applications. -
Bacteria Antibiotic
Nogalamycin is an anthracyclinone antibiotic that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity along with cytotoxic effects against specific tumor cells. Derived from Streptomyces nogalater var. nogalater, Nogalamycin selectively inhibits RNA synthesis by binding to the DNA template. This compound is valuable for research into anticancer therapeutics and bacterial resistance mechanisms. -
Ansamycin Antibiotic
Rifamycin is an orally active ansamycin antibiotic that primarily inhibits DNA-dependent RNA synthesis. It demonstrates significant antibacterial activity against Mycobacterium tuberculosis and can also affect hepatic bile acid metabolism. Additionally, Rifamycin exhibits anti-inflammatory properties, making it useful in the study of infections caused by Mycobacterium tuberculosis and Bacteroides fragilis, as well as in research involving lipopolysaccharide-induced inflammation. -
Antibiotic
Holomycin is a secondary metabolite belonging to the dithiolopyrrolone class, recognized for its broad-spectrum antibiotic properties. It exhibits notable antitumor activity and functions by inhibiting RNA synthesis in vivo. Holomycin serves as a valuable tool in pharmaceutical research, particularly in studies related to antimicrobial resistance and cancer therapeutics. -
Antibiotic
10,11-Dehydrocurvularin is an antibiotic derived from fungi, known for its ability to activate the heat shock response. This compound exhibits significant inhibition of the TGF-β signaling pathway, demonstrating anti-tumorigenic properties. Its biological activities make it a valuable reagent for research in antibiotic efficacy and cancer biology. -
Antitumor Antibiotic
Dinactin is an antibiotic ionophore derived from Streptomyces species, primarily targeting the Wnt/β-catenin signaling pathway in cancer cells. This compound exhibits significant inhibition of HCT-116 cell proliferation, with an IC50 value of 1.1 μM, demonstrating its anti-proliferative effects in an apoptosis-independent manner. Additionally, Dinactin serves as a valuable tool in research related to neuropathic pain. -
Antitumor Antibiotic
Sibiromycin is a glycosylated pyrrolobenzodiazepine (PBD) that functions as a potent antitumor antibiotic. It exerts its biological activity by covalently binding to DNA in the minor groove, specifically targeting the amino group of guanine. This mechanism contributes to its effectiveness in cancer research, making it a valuable tool for studies involving DNA interactions and antitumor mechanisms. -
Antineoplastic Antibiotic
Cytogenin, an antineoplastic antibiotic, demonstrates significant antitumor activity by inhibiting the growth of Ehrlich ascites tumors in mouse models. This compound also regulates inflammatory cytokines, effectively reducing levels of inducible nitric oxide synthase (iNOS), nitric oxide (NO), and interleukin-6 (IL-6) in murine macrophages. Additionally, Cytogenin exhibits antidiabetic effects, making it a valuable reagent for research in cancer biology and inflammation. -
Antibiotic
Fostriecin is a triene antibiotic that primarily targets topoisomerase II and inhibits protein phosphatase PP2A. It exhibits potent antibacterial activity and has been employed in research focused on mechanisms of antibiotic resistance and cancer therapy. Its unique mechanism of action makes it a valuable tool for studying cellular processes related to gene expression and cell cycle regulation. -
Antibiotic
Tigecycline hydrochloride is a broad-spectrum glycylcycline antibiotic that primarily targets bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits significant antibacterial activity against a variety of gram-positive and gram-negative pathogens, including Escherichia coli and Acinetobacter baumannii, with mean inhibitory concentrations (MIC) of approximately 125 ng/mL for E. coli and MIC50 and MIC90 values of 1 and 2 mg/L for A. baumannii, respectively. Tigecycline hydrochloride is commonly used in research settings to investigate antibiotic resistance mechanisms and to study the efficacy of antimicrobial agents. -
Antibiotic
DCAP is a broad-spectrum antibiotic that targets the membranes of both Gram-positive and Gram-negative bacteria. It exhibits significant antibacterial activity by disrupting autophagic processes, specifically blocking the maturation of autophagolysosomes and interrupting autophagic flux. This compound is utilized in research applications focused on bacterial infections and autophagy regulation. -
Antibiotic
Ascochlorin is an isoprenoid antibiotic that primarily targets the STAT3 signaling cascade, leading to the suppression of tumor growth. It has demonstrated the ability to induce apoptosis in cancer cells while exhibiting anti-inflammatory properties. This compound is valuable for research applications focusing on cancer biology, inflammation, and the modulation of intracellular signaling pathways. -
Antitumor Antibiotic
Peplomycin is an analog of bleomycin that functions as an antitumor antibiotic. It demonstrates significant antitumor activity while exhibiting lower pulmonary toxicity compared to its parent compound. Peplomycin is known to induce apoptosis in oral squamous cell carcinoma (SSCKN) cells and may lead to skin abnormalities and pulmonary fibrosis. This compound is valuable for research related to tumors, pulmonary fibrosis, and associated diseases. -
Antibiotic Agent
Nargenicin A1 is an antibiotic agent primarily targeting Gram-positive bacteria. It exhibits anti-inflammatory properties and has been shown to protect HINAE cells from DNA damage and apoptosis induced by Tacrolimus. Additionally, Nargenicin A1 is relevant for research applications related to acute myeloid leukemia, making it a valuable compound for studies in both infection and cancer biology. -
Antibiotic
Undecylprodigiosin is an antibiotic derived from the prodiginine family, known for its potent antibacterial properties. It has been shown to selectively induce apoptosis in human breast carcinoma cells independently of the p53 pathway, demonstrating its potential as an anticancer agent. Additionally, undecylprodigiosin possesses immunosuppressive and antimicrobial activities, making it a valuable tool in cancer research and antimicrobial studies. -
Antibiotic
Arisostatin A is a microbial secondary metabolite with antibiotic activity specifically against Gram-positive bacteria. It exhibits potent anti-tumor effects by inducing apoptosis through the activation of caspase-3 and the generation of reactive oxygen species (ROS) in AMC-HN-4 cells. This compound is valuable for research applications in cancer biology and antimicrobial studies. -
Antifungal Antibiotic
Filipin complex is a potent polyene macrolide antifungal antibiotic that primarily targets membrane cholesterol. By inserting into cellular membranes, it sequesters cholesterol, thereby inhibiting the entry of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). The complex comprises approximately 75.8% Filipin III, 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I, making it a valuable tool in antifungal research and viral entry studies. Its characteristic fluorescence spectrum (Ex/Em = 380/430 nm) further enhances its utility in biological applications. -
Antibiotic
Nourseothricin sulfate is a broad-spectrum antibiotic that targets the outer membrane of Gram-negative bacteria, effectively disrupting their integrity. This compound inhibits protein biosynthesis in prokaryotic cells and demonstrates significant antifungal activity against eukaryotic organisms. It is widely utilized as a selective marker in various applications, including the transformation of bacteria, yeast, filamentous fungi, and plant cells, facilitating research in microbiology and molecular biology. -
Antibiotic
Aurachin D is an antibiotic that primarily targets Gram-positive bacteria and certain fungi. It functions by inhibiting NADH oxidation in beef heart submitochondrial particles, which disrupts cellular respiration and energy production. This compound is valuable for research applications focused on understanding bacterial and fungal resistance mechanisms as well as exploring metabolic pathways. -
Antifungal Antibiotic/Complex III Inhibitor
Myxothiazol is an antifungal antibiotic that acts as an inhibitor of mitochondrial electron transport chain complex III (bc1 complex). It demonstrates potent antifungal activity against various yeasts and fungi, exhibiting effective growth inhibition at concentrations ranging from 0.01 to 3 μg/ml. This compound is valuable for research applications focused on mitochondrial function and the mechanisms of antifungal resistance. -
Antibiotic Fungicide
Validamycin A acts as an antibiotic fungicide primarily targeting fungal pathogens. Isolated from Streptomyces hygroscopicus var. limoneus, it exhibits significant inhibitory effects against Aspergillus flavus, with a minimum inhibitory concentration (MIC) of 1 µg/mL. Additionally, Validamycin A demonstrates potent inhibition of trehalase in Rhizoctonia solani, with an IC50 value of 72 µM. It also functions as a reversible inhibitor of tyrosinase, exhibiting a Ki value of 5.893 mM, making it a valuable reagent for agricultural and biochemical research applications.
