3,9-Dimethyl-3,9-diazaspiro[5.5]undecane is a rigid linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates targeted protein degradation, exemplified by its application in creating potent IRAK4 PROTAC degraders, such as FIP22, which demonstrate efficacy in conditions like atopic dermatitis. Its structural characteristics enhance the stability and specificity of PROTAC development, making it a valuable tool in chemical biology research.
3,9-Dimethyl-3,9-diazaspiro[5.5]undecane is a rigid linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates targeted protein degradation, exemplified by its application in creating potent IRAK4 PROTAC degraders, such as FIP22, which demonstrate efficacy in conditions like atopic dermatitis. Its structural characteristics enhance the stability and specificity of PROTAC development, making it a valuable tool in chemical biology research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
![3,9-Dimethyl-3,9-diazaspiro[5.5]undecane 93004-48-9 PROTAC Linker](https://www.adooq.com/media/catalog/product/cache/9222bce87e7def4079ba2ab8616be292/a/8/a82165-3-9-dimethyl-3-9-diazaspiro-5-5-undecane.gif)
