4-Epianhydrotetracycline hydrochloride

Catalog No.: A32246
Antibiotic
4-Epianhydrotetracycline hydrochloride is an antibiotic that serves as a significant intermediate in tetracycline synthesis. It demonstrates cytotoxic effects and induces apoptosis in zebrafish embryos, highlighting its potential for developmental toxicology studies. Furthermore, it exhibits antimicrobial activity against Shewanella, Escherichia coli, and Pseudomonas aeruginosa, with minimum inhibitory concentrations of 2 mg/L, 1 mg/L, and 64 mg/L, respectively, indicating its utility in microbial resistance research.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
Description4-Epianhydrotetracycline hydrochloride is an antibiotic that serves as a significant intermediate in tetracycline synthesis. It demonstrates cytotoxic effects and induces apoptosis in zebrafish embryos, highlighting its potential for developmental toxicology studies. Furthermore, it exhibits antimicrobial activity against Shewanella, Escherichia coli, and Pseudomonas aeruginosa, with minimum inhibitory concentrations of 2 mg/L, 1 mg/L, and 64 mg/L, respectively, indicating its utility in microbial resistance research.
Product Information
Catalog NumA32246
FormulaC22H23ClN2O7
Molecular Weight462.88
CAS Number4465-65-0
SMILESO[C@@](C(C1=C(C2=C3O)O)=O)(C(C(C(N)=O)=C4O)=O)[C@](CC1=C(C2=CC=C3)C)([H])[C@H]4N(C)C.Cl
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