Catalog No.
Product Name
Application
Product Information
Citations
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Cannabinoid Receptor
1-(1-Methyl-1H-indol-3-yl)-2-(1-naphthalenyl)ethanone functions as a potent agonist at cannabinoid receptors, providing insight into cannabinoid signaling pathways. This compound exhibits significant biological activity, making it valuable for research applications in the exploration of endocannabinoid system interactions, pharmacology, and potential therapeutic effects. Its structural resemblance to known synthetic cannabinoids adds to its relevance in studies of cannabinoid receptor modulation. -
CB1 Receptor Antagonist
PF-514273 is a highly selective antagonist of the cannabinoid-1 receptor (CB1), exhibiting an IC50 of 1 nM. This compound demonstrates notable efficacy in reducing food intake in murine models, making it a valuable tool for obesity research. PF-514273 can be utilized to explore the role of CB1 signaling in appetite regulation and related metabolic disorders. -
Cannabinoid Derivative
ADB-BICA is a synthetic cannabinoid derivative that acts primarily on the cannabinoid receptors in the endocannabinoid system. It exhibits key biological activity by modulating receptor signaling, which is essential for research in areas such as neuropharmacology and therapeutic potential of cannabinoids. This compound is utilized to study the effects of cannabinoids on various physiological processes and is valuable in the exploration of cannabinoid-based treatments. -
Cannabinoid-like Analog
BZO-CHMOXIZID is a cannabinoid-like analog that primarily targets cannabinoid receptors. This compound modulates the endocannabinoid system, demonstrating potential anxiolytic and analgesic effects. BZO-CHMOXIZID can be utilized in research applications focusing on neuropharmacology, pain management, and therapeutic mechanisms of cannabinoids. -
Cannabinoid Derivative
Azidoindolene 1 is a cannabinoid derivative that functions as an analog in various biological studies. It exhibits potential activity at cannabinoid receptors, making it relevant for research into endocannabinoid signaling pathways. This compound is useful for investigations into the physiological effects of cannabinoids and their therapeutic applications. -
Anandamide Analog
Arachidonoyl 2'-fluoroethylamide is an anandamide analog that specifically targets cannabinoid receptors. This compound exhibits significant biological activity, influencing endocannabinoid signaling pathways, and has potential applications in research focused on intraocular hypertension. Studies may explore its effects on ocular pressure regulation and its therapeutic implications for related conditions. -
Phytocannabinoid Metabolite
(±)-6',7'-Epoxy cannabichromene is a phytocannabinoid metabolite that selectively interacts with various cannabinoid receptors in the endocannabinoid system. This compound showcases notable biological activity, including modulation of pain and inflammation pathways. Research applications include exploring its potential therapeutic effects in neurological disorders and understanding the pharmacological properties of cannabinoid derivatives. -
BB-22 Metabolite
BB-223-carboxyindole metabolite is a metabolite of the synthetic cannabinoid BB-22. As an analog of cannabinoids, it primarily interacts with the endocannabinoid system. This compound is significant for researchers studying cannabinoid metabolism and its physiological effects, providing insights into cannabinoid receptor interactions and their potential therapeutic applications. -
Cannabinoid Receptor
5-Fluoro PB-22 8-hydroxyisoquinoline isomer primarily targets cannabinoid receptors, exerting effects relevant to cannabinoid signaling pathways. This compound exhibits biological activity that may be useful in studies investigating the endocannabinoid system and its role in various physiological processes. Research applications include the exploration of cannabinoid receptor modulation, potential therapeutic effects, and the investigation of synthetic cannabinoid mechanisms of action. -
CB1 Positive Allosteric Modulator (PAM)
GAT229 is a positive allosteric modulator of the CB1 receptor, demonstrating significant potential in the reduction of intraocular pressure (IOP). Research indicates that GAT229 effectively enhances CB1 receptor-mediated IOP-lowering effects in high IOP mouse models. A solution of 0.2% GAT229 or administration at a dosage of 10 mg/kg results in notable IOP reduction, making it a valuable tool for studies focused on glaucoma and related conditions associated with elevated intraocular pressure. -
Phytocannabinoid Metabolite
6',7'-Epoxy cannabigerol is a phytocannabinoid metabolite that functions primarily as an active compound influencing cannabinoid receptor activity. This compound demonstrates potential biological activity associated with modulating neurotransmitter release and exhibiting anti-inflammatory properties. It is of particular interest in research applications focused on the therapeutic effects of cannabinoids and their mechanisms in various biological systems. -
Phytocannabinoid Derivative
11-Nor-9(R)-carboxy-hexahydrocannabinol is a phytocannabinoid derivative that interacts with the endocannabinoid system, specifically targeting cannabinoid receptors. This compound exhibits biological activity similar to other known cannabinoids, making it relevant for research into pain management, inflammation, and neuroprotection. It serves as a valuable tool for studies focused on the pharmacological effects of cannabinoids and their potential therapeutic applications. -
Cannabinoid Derivative
5-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic derivative of cannabinoids that selectively targets cannabinoid receptors. This compound exhibits notable biological activity by modulating receptor signaling pathways, making it valuable for research on cannabinoid receptor pharmacology. Its applications include studying the effects of cannabinoids on neuronal signaling and the exploration of therapeutic possibilities within the endocannabinoid system. -
Cannabinoid
MDMB-FUBINACA metabolite M1 is a synthetic cannabinoid that acts primarily on cannabinoid receptors. This metabolite exhibits significant affinity for CB1 and CB2 receptors, contributing to its biological activity in modulating cannabinoid signaling pathways. It serves as a valuable tool in research focused on the pharmacological effects of cannabinoids and the study of cannabinoid receptor interactions. -
Phytocannabinoid Derivative
Δ4(8)-iso-THC is a phytocannabinoid derivative that shares structural similarities with established cannabinoids. It interacts with cannabinoid receptors, exhibiting potential neuroprotective and anti-inflammatory properties. Research applications include studying the endocannabinoid system and exploring therapeutic avenues for neurological disorders and pain management. -
Cannabinoid Receptor Control
5Br-INACA is a synthetic cannabinoid precursor targeting cannabinoid receptors. It plays a crucial role in the production of cannabinoids for research applications involving the endocannabinoid system. Its use facilitates the exploration of cannabinoid receptor modulation and the investigation of related biological pathways. 5Br-INACA is valuable for studies aimed at understanding the pharmacological effects of cannabinoids in various biological contexts. -
Hexahydrocannabinol Metabolites
8(R)-Hydroxy-9(S)-Hexahydrocannabinol is a key metabolite of hexahydrocannabinol (HHC), interacting with cannabinoid receptors in the endocannabinoid system. This compound is of significant interest in pharmacological research for its potential therapeutic effects and metabolism of cannabinoids. It serves as a valuable tool in studying the pharmacokinetics and biological activity of HHC metabolites in various biological contexts. -
Phytocannabinoid Derivative
Dehydrocannabifuran is a phytocannabinoid derivative that interacts with cannabinoid receptors, primarily targeting the CB1 and CB2 receptors. This compound exhibits anti-inflammatory and analgesic properties, making it a valuable tool for research in pain management and inflammatory conditions. Its unique chemical structure and biological activities facilitate studies on cannabinoid mechanisms and therapeutic potential. -
Phytocannabinoid Derivative
11-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid derivative with notable affinity for cannabinoid receptors. This compound is primarily studied for its potential analgesic and anti-inflammatory properties, making it valuable in research focused on pain management and neuroprotection. Its metabolic pathways and interactions can provide insights into the therapeutic potential of cannabinoids in various biological systems. -
Phytocannabinoid
10α-Hydroxy-Δ8-THC is a phytocannabinoid that acts primarily on cannabinoid receptors. This compound demonstrates a range of biological activities, including potential analgesic and anti-inflammatory effects. It serves as a valuable tool for research in the fields of pharmacology and neuroscience, particularly in studies related to the therapeutic applications of cannabinoids. -
Phytocannabinoid Metabolite
11-Hydroxy-9(S)-hexahydrocannabinol is a phytocannabinoid metabolite known for its interaction with the endocannabinoid system. This compound exhibits significant biological activity, particularly in modulating cannabinoid receptors, which may influence various physiological processes such as pain perception, mood regulation, and appetite. It is primarily utilized in research related to cannabinoid pharmacology, therapeutic applications of cannabis, and the study of metabolic pathways of cannabinoids. -
CB1/CB2 Receptor Agonist
SAD448 is an agonist of the CB1 and CB2 receptors. It has demonstrated the ability to lower intraocular pressure (IOP), making it a valuable compound for research in ocular health and cannabinoid-mediated signaling pathways. This compound is relevant for studies investigating the therapeutic potential of cannabinoid receptor modulation in various conditions, including glaucoma and other diseases affecting intraocular pressure. -
CB1R/AMPK Modulator
CB1R/AMPK Modulator 1 is a potent modulator of the cannabinoid receptor type 1 (CB1R) and adenosine monophosphate-activated protein kinase (AMPK), exhibiting a Ki of 0.81 nM and an IC50 of 3.9 nM for CB1R. This compound effectively activates AMPK, leading to significant reductions in food intake and body weight. Additionally, it enhances glucose tolerance and insulin sensitivity, making it a valuable tool for research in metabolic disorders and obesity-related studies. -
Phytocannabinoid Derivative
Cannabigerol diacetate is a phytocannabinoid derivative that modulates cannabinoid receptors in the endocannabinoid system. This compound exhibits potential anti-inflammatory and neuroprotective activities, making it an important tool for studying the therapeutic effects of cannabinoids. Its unique structural properties also allow for exploration in various research applications, including pain management and the effects of cannabinoids on neurological disorders. -
Cannabinoid Derivative
CH-FUBIATA is a synthetic cannabinoid derivative with a specific affinity for cannabinoid receptors. This compound demonstrates significant biological activity, impacting pathways involved in pain modulation, appetite regulation, and neuroprotection. CH-FUBIATA is applicable in research focusing on endocannabinoid system modulation, toxicological assessments, and the therapeutic potential of cannabinoids in various diseases. -
cannabinoid
Bzo-poxizid is a synthetic cannabinoid that primarily targets cannabinoid receptors in the central nervous system. This compound exhibits psychoactive properties, making it relevant for studies investigating endocannabinoid modulation and its effects on behavior. Bzo-poxizid may also be utilized in research applications focused on the therapeutic potential of cannabinoids in various neurological disorders. -
Cannabinoids Precursor
2-(2-Chlorophenyl)-1-(1H-indol-3-yl)ethanone is a key precursor in the synthesis of synthetic cannabinoids. This compound plays an essential role in the development of novel cannabinoid derivatives that may be used in pharmacological research. Its ability to modify cannabinoid structures makes it valuable for studies examining cannabinoid receptor interactions and their physiological effects. -
Cannabinoid-type Compounds
(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-type compound that demonstrates significant cannabinoid-like activity in animal models, specifically in dogs and mice. This compound may be of interest for research exploring the therapeutic effects and pharmacological mechanisms of cannabinoids. Its efficacy in modulating cannabinoid receptors makes it a valuable tool for studies in areas such as pain relief, anxiety reduction, and other neuropsychopharmacological applications. -
Phytocannabinoid Metabolite
5'-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid metabolite that serves as a significant derivative of cannabinoids. It is known to exhibit potential psychoactive properties and interact with the endocannabinoid system. This compound may be utilized in research related to neuropharmacology, cannabinoid receptor studies, and the investigation of cannabis metabolites in biological systems. -
CB2 Receptor Ligand
Δ8-THC methyl ether is a selective ligand for the CB2 receptor, exhibiting a favorable docking score of -10.167 kcal/mol. This compound demonstrates significant antinociceptive activity in murine models, highlighting its potential for research in pain management and cannabinoid receptor studies. Further investigation into its pharmacological properties may support its application in the development of therapeutics targeting the endocannabinoid system. -
Cannabinoid Derivative
2-Fluoro QMPSB is a cannabinoid derivative that acts as a selective modulator of the cannabinoid receptors. This compound exhibits potent biological activity, making it useful for studying cannabinoid receptor mechanisms in research applications related to neuropharmacology and therapeutic developments. Its structural similarity to established synthetic cannabinoids provides valuable insights into cannabinoid receptor interactions and signaling pathways. -
Oxopyridine Carboxamide
CHO-4′Me-5′Br-FUBOXPYRA is an oxopyridine carboxamide that interacts with cannabinoid receptors CB1 and CB2. This compound exhibits limited activation potential, making it a valuable tool for studying the pharmacological properties of synthetic cannabinoids. Its unique structural features support research applications in cannabinoid receptor signaling and the development of cannabinoid-related therapies. -
Phytocannabinoid Derivative
(±)-9α-Hydroxy hexahydrocannabinol is a phytocannabinoid derivative that exhibits interactions with cannabinoid receptors in the endocannabinoid system. This compound has been explored for its potential therapeutic effects, including analgesic and anti-inflammatory properties. It serves as a valuable tool in research focused on understanding the pharmacological profiles of cannabinoids and their effects on various biological pathways. -
CB2 Receptor Agonist
PF-03550096 is an orally active synthetic cannabinoid that selectively targets peripheral CB2 receptors, exhibiting a Ki value of 7.9 nM. This compound demonstrates notable analgesic activity, making it useful for research applications related to pain modulation and inflammation. Its selective action on CB2 receptors enhances its potential for studying cannabinoid-based therapies in various physiological contexts. -
Cannabinoid Derivative
Afubiata is a cannabinoid derivative that interacts with the cannabinoid receptors in the endocannabinoid system. This compound exhibits potential biological activity related to modulating pain, inflammation, and neuroprotection. Afubiata is suitable for research applications focused on cannabinoid receptor mechanisms and the therapeutic effects of cannabinoids in various physiological processes. -
Phytocannabinoid Derivative
8(S)-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid derivative with a unique structural profile resembling known cannabinoids. This compound exhibits significant biological activity, including potential interaction with cannabinoid receptors, which makes it a valuable tool in cannabis research. It is applicable in studies investigating the therapeutic effects of cannabinoids, including pain relief and anti-inflammatory properties. -
Cannabinoid Derivative
(±)-9-Nor-9β-hydroxy Hexahydrocannabinol is a cannabinoid derivative that exhibits pronounced binding affinity for cannabinoid receptors. This compound is utilized in research to investigate the pharmacological effects of cannabinoids, including their influence on pain perception, appetite regulation, and neuroprotection. Its structural similarity to known synthetic cannabinoids makes it a valuable tool for studies focused on cannabinoid interactions and therapeutic potential. -
Cannabinoid Derivative
NAPIE is a cannabinoid derivative that modulates cannabinoid receptors. It exhibits significant biological activity in the endocannabinoid system, which is pivotal for studying the therapeutic potential of cannabinoids. NAPIE is primarily used in research applications related to neurobiology, pain management, and the exploration of cannabinoid signaling pathways. Its structural similarity to existing synthetic cannabinoids makes it a valuable tool for further investigations in cannabinoid biology. -
Cannabinoid Derivative
2-(1-(4-Fluorobenzyl)-1H-indol-3-yl)acetic acid is a cannabinoid derivative that interacts with cannabinoid receptors in the endocannabinoid system. This compound exhibits analgesic and anti-inflammatory properties, making it valuable for research in pain management and inflammation pathways. It serves as a useful tool in studying the pharmacological effects of cannabinoid-like substances. -
CB1/CB2 Agonist
PSB-SB1202 is a phenyl coumarin compound that acts as a dual agonist for the cannabinoid receptors CB1 and CB2. It demonstrates high biological activity with EC50 values of 56 nM for CB1 and 14 nM for CB2, alongside Ki values of 32 nM and 49 nM, respectively. This compound is suitable for research applications focused on the endocannabinoid system and its implications in various physiological processes. -
Δ9,11-THC Analogue
exo-Tetrahydrocannabivarin is a Δ9,11-THC analogue that demonstrates weak binding affinity for cannabinoid receptors (CB) with an IC50 of 1.4 μM. Its biological activity includes effects on motor functions and analgesia, as evidenced in preclinical models using mice. This compound is valuable for research investigating cannabinoid receptor interactions and their implications in pain management and motor control studies. -
Cannabinoid Receptor Antagonist
Giminabant is a cannabinoid receptor antagonist that primarily targets CB1 receptors. It has been shown to modulate endocannabinoid signaling, making it a useful compound for studying metabolic diseases and addiction-related disorders. Its application in research may provide insights into therapeutic approaches for obesity and substance dependence. -
Phytocannabinoid Derivative
Δ8-THCPA-A is a derivative of Δ8-Tetrahydrocannabiphorolic acid, designed to modulate cannabinoid receptors due to its structural similarities to known phytocannabinoids. This compound exhibits significant biological activity, contributing to research on the endocannabinoid system and its implications in therapeutic applications. It serves as a valuable tool for exploring the pharmacological effects and potential medicinal uses of cannabinoids in various biomedical studies. -
Phytocannabinoid Metabolite
Carmagerol is a phytocannabinoid metabolite that interacts with the endocannabinoid system, primarily influencing cannabinoid receptor activity. It exhibits potential neuroprotective and anti-inflammatory properties, making it a valuable compound for research into its effects on pain management and neurological disorders. Carmagerol can be utilized in studies investigating the therapeutic applications of cannabinoids and their metabolites in various biological models. -
Phytocannabinoid Derivative
8(R)-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid derivative that acts as a metabolite of 9(R)-Hexahydrocannabinol. This compound exhibits notable biological activities related to cannabinoid receptor modulation, which may be relevant for studies on cannabinoid pharmacology. It is primarily utilized in research focusing on the therapeutic potential of cannabinoids in various physiological and pathological processes. -
Phytocannabinoid Metabolite
(±)-8'-Hydroxy cannabichromene is a phytocannabinoid metabolite that acts on the endocannabinoid system. It exhibits potential biological activity by interacting with cannabinoid receptors, which may influence various physiological processes. This compound is primarily utilized in research applications focused on cannabis pharmacology, cannabinoid receptor signaling, and the therapeutic effects of cannabinoids. -
Cannabinoid Derivative
5-Fluoro PB-22 N-(2-fluoropentyl) isomer is a synthetic cannabinoid derivative that selectively targets cannabinoid receptors. This compound exhibits potent agonistic activity, making it valuable for research into cannabinoid receptor signaling pathways and their physiological effects. Its unique structure allows for the exploration of cannabinoid-related research applications, including studies related to neuropharmacology and the endocannabinoid system. -
Phytocannabinoid
Tetrahydrocannabiphorol (THCP) is a phytocannabinoid that exhibits potent binding affinity for cannabinoid receptors, specifically CB1 and CB2. This compound has been shown to possess significant analgesic and anti-inflammatory properties, making it a valuable tool for researching pain management and therapeutic applications related to cannabinoid signaling pathways. THCP is of interest in studies examining the efficacy of cannabinoids in various health conditions and may offer insights into the pharmacological potential of cannabis-derived compounds. -
CB1 Agonist
AM11542 is a selective orthosteric agonist of cannabinoid receptor 1 (CB1), exhibiting a reported binding affinity (Ki) of 0.11 nM. This compound facilitates the study of CB1 receptor activation and provides insights into the mechanisms of allosteric modulation. Its application is valuable in exploring the physiological roles of CB1 in various biological pathways and potential therapeutic targets in cannabinoid research. -
Biochemical Reagent
CH-PIATA is a synthetic cannabinoid characterized by an acetamide linker, serving as a biochemical reagent in research applications. This compound exhibits potential biological activity, with EC50 values of >71 nM and >176 nM for cannabinoid receptors CB1 and CB2, respectively. CH-PIATA can be effectively detected as a parent substance in biological samples, making it a useful tool for studying cannabinoid receptor interactions and their physiological roles.
