Catalog No.
Product Name
Application
Product Information
Citations
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BB-22 Metabolite
BB-223-carboxyindole metabolite is a metabolite of the synthetic cannabinoid BB-22. As an analog of cannabinoids, it primarily interacts with the endocannabinoid system. This compound is significant for researchers studying cannabinoid metabolism and its physiological effects, providing insights into cannabinoid receptor interactions and their potential therapeutic applications. -
Cannabinoid Receptor
5-Fluoro PB-22 8-hydroxyisoquinoline isomer primarily targets cannabinoid receptors, exerting effects relevant to cannabinoid signaling pathways. This compound exhibits biological activity that may be useful in studies investigating the endocannabinoid system and its role in various physiological processes. Research applications include the exploration of cannabinoid receptor modulation, potential therapeutic effects, and the investigation of synthetic cannabinoid mechanisms of action. -
CB1 Positive Allosteric Modulator (PAM)
GAT229 is a positive allosteric modulator of the CB1 receptor, demonstrating significant potential in the reduction of intraocular pressure (IOP). Research indicates that GAT229 effectively enhances CB1 receptor-mediated IOP-lowering effects in high IOP mouse models. A solution of 0.2% GAT229 or administration at a dosage of 10 mg/kg results in notable IOP reduction, making it a valuable tool for studies focused on glaucoma and related conditions associated with elevated intraocular pressure. -
Phytocannabinoid Metabolite
6',7'-Epoxy cannabigerol is a phytocannabinoid metabolite that functions primarily as an active compound influencing cannabinoid receptor activity. This compound demonstrates potential biological activity associated with modulating neurotransmitter release and exhibiting anti-inflammatory properties. It is of particular interest in research applications focused on the therapeutic effects of cannabinoids and their mechanisms in various biological systems. -
Phytocannabinoid Derivative
11-Nor-9(R)-carboxy-hexahydrocannabinol is a phytocannabinoid derivative that interacts with the endocannabinoid system, specifically targeting cannabinoid receptors. This compound exhibits biological activity similar to other known cannabinoids, making it relevant for research into pain management, inflammation, and neuroprotection. It serves as a valuable tool for studies focused on the pharmacological effects of cannabinoids and their potential therapeutic applications. -
Cannabinoid Derivative
5-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic derivative of cannabinoids that selectively targets cannabinoid receptors. This compound exhibits notable biological activity by modulating receptor signaling pathways, making it valuable for research on cannabinoid receptor pharmacology. Its applications include studying the effects of cannabinoids on neuronal signaling and the exploration of therapeutic possibilities within the endocannabinoid system. -
Cannabinoid
MDMB-FUBINACA metabolite M1 is a synthetic cannabinoid that acts primarily on cannabinoid receptors. This metabolite exhibits significant affinity for CB1 and CB2 receptors, contributing to its biological activity in modulating cannabinoid signaling pathways. It serves as a valuable tool in research focused on the pharmacological effects of cannabinoids and the study of cannabinoid receptor interactions. -
Phytocannabinoid Derivative
Δ4(8)-iso-THC is a phytocannabinoid derivative that shares structural similarities with established cannabinoids. It interacts with cannabinoid receptors, exhibiting potential neuroprotective and anti-inflammatory properties. Research applications include studying the endocannabinoid system and exploring therapeutic avenues for neurological disorders and pain management. -
Cannabinoid Receptor Control
5Br-INACA is a synthetic cannabinoid precursor targeting cannabinoid receptors. It plays a crucial role in the production of cannabinoids for research applications involving the endocannabinoid system. Its use facilitates the exploration of cannabinoid receptor modulation and the investigation of related biological pathways. 5Br-INACA is valuable for studies aimed at understanding the pharmacological effects of cannabinoids in various biological contexts. -
Hexahydrocannabinol Metabolites
8(R)-Hydroxy-9(S)-Hexahydrocannabinol is a key metabolite of hexahydrocannabinol (HHC), interacting with cannabinoid receptors in the endocannabinoid system. This compound is of significant interest in pharmacological research for its potential therapeutic effects and metabolism of cannabinoids. It serves as a valuable tool in studying the pharmacokinetics and biological activity of HHC metabolites in various biological contexts. -
Phytocannabinoid Derivative
Dehydrocannabifuran is a phytocannabinoid derivative that interacts with cannabinoid receptors, primarily targeting the CB1 and CB2 receptors. This compound exhibits anti-inflammatory and analgesic properties, making it a valuable tool for research in pain management and inflammatory conditions. Its unique chemical structure and biological activities facilitate studies on cannabinoid mechanisms and therapeutic potential. -
Phytocannabinoid Derivative
11-Hydroxy-9(R)-hexahydrocannabinol is a phytocannabinoid derivative with notable affinity for cannabinoid receptors. This compound is primarily studied for its potential analgesic and anti-inflammatory properties, making it valuable in research focused on pain management and neuroprotection. Its metabolic pathways and interactions can provide insights into the therapeutic potential of cannabinoids in various biological systems. -
Phytocannabinoid
10α-Hydroxy-Δ8-THC is a phytocannabinoid that acts primarily on cannabinoid receptors. This compound demonstrates a range of biological activities, including potential analgesic and anti-inflammatory effects. It serves as a valuable tool for research in the fields of pharmacology and neuroscience, particularly in studies related to the therapeutic applications of cannabinoids. -
Phytocannabinoid Metabolite
11-Hydroxy-9(S)-hexahydrocannabinol is a phytocannabinoid metabolite known for its interaction with the endocannabinoid system. This compound exhibits significant biological activity, particularly in modulating cannabinoid receptors, which may influence various physiological processes such as pain perception, mood regulation, and appetite. It is primarily utilized in research related to cannabinoid pharmacology, therapeutic applications of cannabis, and the study of metabolic pathways of cannabinoids. -
CB1/CB2 Receptor Agonist
SAD448 is an agonist of the CB1 and CB2 receptors. It has demonstrated the ability to lower intraocular pressure (IOP), making it a valuable compound for research in ocular health and cannabinoid-mediated signaling pathways. This compound is relevant for studies investigating the therapeutic potential of cannabinoid receptor modulation in various conditions, including glaucoma and other diseases affecting intraocular pressure. -
CB1R/AMPK Modulator
CB1R/AMPK Modulator 1 is a potent modulator of the cannabinoid receptor type 1 (CB1R) and adenosine monophosphate-activated protein kinase (AMPK), exhibiting a Ki of 0.81 nM and an IC50 of 3.9 nM for CB1R. This compound effectively activates AMPK, leading to significant reductions in food intake and body weight. Additionally, it enhances glucose tolerance and insulin sensitivity, making it a valuable tool for research in metabolic disorders and obesity-related studies. -
Opioid Receptor
1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid is a selective modulator of opioid receptors. This compound exhibits significant affinity for cannabinoid receptor sites and shows potential in studying the therapeutic effects of cannabinoid modulation. It is primarily used in research exploring the pharmacological effects of synthetic cannabinoids and their metabolites. -
GPR55 Ligand
L-α-lysophosphatidylinositol (Soy) sodium is a potent endogenous ligand for the GPR55 receptor. As a lysophospholipid and endocannabinoid neurotransmitter, it plays a crucial role in various signaling pathways. It is primarily utilized in research applications focusing on cannabinoid receptor modulation, cell signaling processes, and neurobiology studies. -
Active Metabolite of Cannabinol
11-Hydroxy cannabinol is an active metabolite of Cannabinol, primarily targeting cannabinoid receptors in the endocannabinoid system. This compound exhibits biological activity that may influence numerous physiological processes, including pain modulation and anti-inflammatory effects. It is utilized in preclinical research to explore therapeutic applications related to cannabinoid signaling pathways and their potential impact on various health conditions. -
MMB-CHMICA Metabolite
MMB-ICA is a metabolite of MMB-CHMICA, primarily targeting the cannabinoid receptor system. This compound demonstrates significant biological activity in modulating receptor signaling pathways, making it valuable for research in cannabinoid pharmacology. MMB-ICA is utilized in studies investigating the therapeutic potential of cannabinoids and their metabolic pathways. -
PB-22 Metabolite
PB-22 N-(5-Hydroxypentyl)-3-carboxyindole metabolite is a primary metabolite of the cannabinoid PB-22. This compound exhibits biological activity through its interaction with the endocannabinoid system, influencing cannabinoid receptor signaling pathways. It is utilized in research to explore the metabolic pathways of synthetic cannabinoids and their pharmacological effects in various biological systems. -
PB-22 Metabolite
PB-22 N-(4-Hydroxypentyl)-3-carboxyindole metabolite is a significant metabolite of the synthetic cannabinoid PB-22. This compound interacts primarily with cannabinoid receptors, influencing cannabinoid signaling pathways. It is valuable for research applications focused on studying the metabolism and pharmacological effects of cannabinoids, as well as providing insights into potential therapeutic uses and regulatory impacts associated with cannabinoid exposure. -
MMB-CHMICA Metabolite
AB-INACA is a metabolite of the synthetic cannabinoid AB-CHMINACA, acting primarily on the cannabinoid receptors. This compound has been utilized in research to investigate synthetic cannabinoid metabolism and receptor interaction dynamics. Its biological activity provides valuable insights into the pharmacological pathways of synthetic cannabinoids, making it a useful tool for toxicological studies and drug metabolism research. -
DAGL-α/DAGL-β Inhibitor
LEI105 is a selective and reversible dual inhibitor of diacylglycerol lipase (DAGL)-α and DAGL-β. This compound effectively decreases levels of 2-arachidonoylglycerol in Neuro2A cells, demonstrating its potential to modulate endocannabinoid signaling. Research applications include investigations into the mechanisms underlying obesity, metabolic disorders, and neuroinflammation, as well as studies of cannabinoid receptor-mediated synaptic plasticity in mouse hippocampal slices. -
Active Metabolite of delta 9-Tetrahydrocannabinol
9α,10α-Epoxyhexahydrocannabinol is an active metabolite of delta 9-tetrahydrocannabinol, primarily targeting cannabinoid receptors. This compound exhibits notable anticonvulsant properties, effectively reducing body temperature and prolonging pentobarbital-induced sleep in animal models. Additionally, it has demonstrated protective effects against pentylenetetrazol-induced seizures, making it valuable for research in seizure disorders and cannabinoid pharmacology. -
TRP Channel Inhibitor
Cannabidiorcol (CBDO) is an inhibitor of transient receptor potential (TRP) channels. This compound, structurally related to cannabidiol with a shortened pentyl side chain, exhibits anti-inflammatory properties while displaying low affinity for cannabinoid receptors. Research applications include investigations into its potential role in modulating inflammation and exploring its effects on tumorigenesis at elevated concentrations. -
ACU Inhibitor/VR1 Agonist
OMDM-5 is a selective anandamide cellular uptake (ACU) inhibitor, exhibiting a Ki of 4.8 μM. In addition, OMDM-5 demonstrates potent activity as a vanilloid receptor type 1 (VR1, TRPV1) agonist, with an EC50 of 75 nM. This compound also shows weak activity as a cannabinoid receptor type 1 (CB1) ligand, with a Ki of 4.9 μM. Its properties make OMDM-5 useful for studies involving pain modulation and endocannabinoid signaling pathways. -
MAGL Inhibitor
OMDM169 is a selective inhibitor of monoacylglycerol lipase (MAGL), effectively increasing the levels of 2-arachidonoylglycerol (2-AG) in biological systems. This compound demonstrates significant analgesic properties through the indirect activation of cannabinoid receptors. OMDM169 exhibits an effective concentration of 0.13 μM, making it a valuable tool for research focused on pain modulation and cannabinoid receptor signaling pathways. -
2-arachidonoylglycerol derivative
1-Monoarachidin is a 2-arachidonoylglycerol derivative that primarily acts as a modulator of cannabinoid receptors. This fatty acid plays a crucial role in the endocannabinoid system, contributing to various biological processes such as inflammation and neuroprotection. It is utilized in research to investigate the physiological effects of endocannabinoids and their potential therapeutic applications in neurological and inflammatory disorders. -
O-Alkyl-N-acyloxy Homologues
Oxy-Arachidonoyl ethanolamide is an O-alkyl-N-acyl oxime derivative that acts on O-Alkyl-N-acyl homologues. This compound exhibits significant biological activity, particularly in the modulation of endocannabinoid systems. It is employed in research applications focusing on cannabinoid receptor signaling, lipid metabolism, and neuroprotective studies, illuminating potential therapeutic pathways for various neurological diseases. -
Endogenous Metabolite
N-Methylarachidonamide is an analog of the endogenous cannabinoid anandamide, primarily targeting the central cannabinoid receptor (CB1). This compound exhibits a binding affinity with a Ki value of 60 nM for CB1, influencing various physiological processes. Additionally, it effectively inhibits rat glial gap junction cell-cell communication by 100% at a concentration of 50 μM. As such, N-Methylarachidonamide is a valuable tool for research exploring cannabinoid receptor signaling and its implications in neurobiology and related fields. -
FAAH Inhibitor
3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone is a potent inhibitor of fatty acid amide hydrolase (FAAH) with a pI50 of 5.89. This compound exhibits significant activity against endocannabinoids and lipid mediators, making it relevant for studies in pain management, inflammation, and cannabinoid signaling pathways. Its limited affinity for cannabinoid receptors CB(1) and CB(2) allows for targeted research into FAAH-related physiological processes without direct receptor modulation. -
N-acylserinol Compound
Myristoyl ethanolamide, an N-acylserinol compound, functions as a bioactive lipid signaling molecule. It is involved in modulating various biological processes, including inflammation and pain perception. Myristoyl ethanolamide serves as a valuable tool in research applications focused on lipid metabolism, neuromodulation, and the study of cannabinoid receptor interactions. This compound can enhance the understanding of endocannabinoid signaling pathways and their implications in physiological and pathological conditions. -
Endogenous Metabolite
Palmitoleoyl ethanolamide (POEA) is an endogenous fatty amide that functions primarily as a signaling molecule through the activation of cannabinoid receptors. It has been shown to exhibit anti-inflammatory and analgesic properties, making it relevant for research in pain management and inflammatory disorders. POEA's involvement in metabolic processes also positions it as a valuable target for studies in obesity and metabolic syndrome. -
Ligand for Target Protein for PROTAC
Rimonabant carboxylic acid is a ligand used for the targeted protein degradation (PROTAC) approach by engaging with the target protein. This compound plays a crucial role in synthesizing PROTAC CB1R Degrader-1, facilitating the study of cannabinoid receptor biology and influencing metabolic processes. It serves as a valuable tool for researchers investigating innovative therapeutic strategies for conditions related to the endocannabinoid system. -
PROTAC Linker
2-[4-(Aminomethyl)triazol-1-yl]ethanamine is a specialized PROTAC linker that serves as a crucial component in targeted protein degradation strategies. This compound facilitates the synthesis of PROTAC CB1R Degrader-1, enabling the effective modulation of cannabinoid receptor 1 (CB1R) levels. Its application in research supports investigations into protein homeostasis and therapeutic approaches for various diseases. -
Lipid
C18:1 Anandamide is an endocannabinoid lipid that primarily targets cannabinoid receptors, particularly CB1 and CB2. It exhibits various biological activities, including modulation of pain, appetite, and mood. C18:1 Anandamide is widely utilized in research focused on the endocannabinoid system, neurobiology, and the therapeutic potential of cannabinoids in a range of physiological processes and disorders. -
Lipid
N-20:4 L-Serine MeEster is a lipid-derived compound that functions as a structural analog of anandamide. It exhibits significant biological activity in modulating cannabinoid receptor signaling pathways, making it a valuable reagent for studying lipid-mediated cellular processes. This compound is useful in various research applications, including investigations of endocannabinoid system dynamics and lipid signaling in neurobiology. -
Lipid
C17:0 Anandamide phosphate sodium is a lipid derivative of anandamide, primarily targeting cannabinoid receptors. This compound possesses bioactive properties that may influence various physiological pathways, making it a valuable tool in studies related to endocannabinoid signaling, lipid metabolism, and neurobiology. Its applications include investigating the role of lipid mediators in inflammation, pain, and neurodegenerative diseases. -
Lipid
C20:4 Anandamide (AEA) is a bioactive lipid that acts as an endocannabinoid, primarily targeting cannabinoid receptors in the central nervous system. This compound is known for its involvement in pain modulation, appetite regulation, and neuroprotection. C20:4 AEA is commonly utilized in research to investigate the physiological effects of endocannabinoids and their potential therapeutic applications in various neurological and inflammatory conditions. -
Biochemical Assay Reagent
Oleoylsulfamide is a selective inhibitor of cannabinoid receptor 1 (CB1). This compound can be utilized as a biochemical assay reagent to investigate the role of CB1 in various physiological processes. It is particularly valuable in studies related to metabolic disorders, pain modulation, and neuroprotection. -
Lipid
C17:1 Anandamide is a synthetic derivative of anandamide, a significant endocannabinoid that interacts primarily with cannabinoid receptors. This compound demonstrates key biological activities, including modulation of pain perception, appetite, and mood regulation. C17:1 Anandamide is useful for studying the endocannabinoid system and its implications in various therapeutic areas, such as neurobiology and pain management. Its unique lipid structure enables investigations into lipid signaling pathways and their role in cellular processes. -
Lipid
NBD AA is a fluorescent analog of anandamide that selectively targets cannabinoid receptors. This compound plays a critical role in lipid signaling pathways and is utilized in studies examining endocannabinoid system functions. Its fluorescent properties make NBD AA an effective tool for visualizing lipid distribution and activity in live cell imaging and various biochemical assays. -
Lipid
N-Arachidonoyl-L-Serine sodium is a lipid compound that acts as an analog of anandamide, a well-known endocannabinoid. This reagent exhibits important biological activities, including the modulation of pain sensation, inflammation, and neuroprotection. It is utilized in research exploring cannabinoid receptor pathways and their therapeutic potential in various neurological and inflammatory disorders. -
Lipid
C18:2 Anandamide phosphate sodium is a phospholipid derivative of anandamide, acting primarily on cannabinoid receptors. This compound exhibits bioactive properties that influence lipid signaling pathways and modulate neuronal communication. It is applicable in research exploring endocannabinoid system dynamics, neuroprotection, and potential therapeutic avenues for neurological disorders. -
Lipid
N-Oleoyl-L-serine sodium is an analog of anandamide that primarily targets lipid signaling pathways. This compound exhibits notable biological activity as a cannabinoid receptor modulator, influencing physiological processes such as pain perception and inflammation. It is frequently used in research applications focused on neurobiology and lipid metabolism. -
Ester Product
(9Z,11E)-Octadecadien ethanolamide is an ester product that serves as a bioactive lipid mediator. It is known to modulate endocannabinoid receptor activity and influences various physiological processes, including pain perception and inflammation. This compound is primarily utilized in research focused on lipid signaling pathways, cannabinoid receptor studies, and neurobiology. -
Biochemical Assay Reagent
NBD AEA is a fluorescent derivative of anandamide (arachidonoylethanolamide) designed for use as a biochemical assay reagent. This compound serves as a valuable tool for studying cannabinoid receptors and endocannabinoid signaling pathways. It enables the visualization and quantification of AEA interactions in various biological systems, facilitating research in pharmacology and neurobiology. -
Synthetic Cannabinoid
5-Fluoropentylindole serves as a synthetic cannabinoid that primarily targets cannabinoid receptors in the central nervous system. This compound exhibits significant affinity for CB1 receptors, making it a valuable tool for studying the endocannabinoid system and its associated signaling pathways. 5-Fluoropentylindole is applicable in pharmacological research and may aid in investigating the effects of synthetic cannabinoids on physiological processes and potential therapeutic outcomes. -
Aminoalkylindole Derivative
7'-Methoxy NABUTIE is a derivative of aminoalkylindole that primarily targets cannabinoid receptors. This compound is recognized for its potential biological activity in modulating the effects associated with alcohol consumption. Research applications include investigations into the pathways of alcohol abuse and the exploration of therapeutic strategies for addiction.
