8-Methyl-4-oxo-N,N-dipropyl-4H-thieno3,2-cchromene-2-carboxamide

Catalog No.: A99777
Drug Intermediate
8-Methyl-4-oxo-N,N-dipropyl-4H-thieno[3,2-c]chromene-2-carboxamide serves as a critical drug intermediate in the synthesis of pyruvate kinase inhibitors. This compound is instrumental in the development of therapeutic agents targeting metabolic pathways, particularly in cancer research, where modulation of pyruvate kinase activity may influence tumor growth and survival. Its utility in synthetic biology allows for the exploration of novel treatments aimed at metabolic dysregulation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description8-Methyl-4-oxo-N,N-dipropyl-4H-thieno[3,2-c]chromene-2-carboxamide serves as a critical drug intermediate in the synthesis of pyruvate kinase inhibitors. This compound is instrumental in the development of therapeutic agents targeting metabolic pathways, particularly in cancer research, where modulation of pyruvate kinase activity may influence tumor growth and survival. Its utility in synthetic biology allows for the exploration of novel treatments aimed at metabolic dysregulation.
Product Information
Catalog NumA99777
FormulaC19H21NO3S
Molecular Weight343.44
CAS Number902516-53-4
SMILESO=C1OC2=C(C3=C1C=C(C(N(CCC)CCC)=O)S3)C=C(C)C=C2
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